Acta Scientific Ophthalmology (ISSN: 2582-3191)

Case Report Volume 5 Issue 2

Bilateral Metastatic Acute Lymphoblastic Leukaemia Presenting as Hypopyon: A Case Report

Asmita Indurkar, Manoj Soman, Sameer Iqbal*, Sumita Phatak and Unnikrishnan Nair R

Department of Vitreo-Retinal Service, Chaithanya Eye Hospital and Research Institute, Thiruvananthapuram, Kerala, India

*Corresponding Author: Sameer Iqbal, Department of Vitreo-Retinal Service, Chaithanya Eye Hospital and Research Institute, Thiruvananthapuram, Kerala, India.

Received: December 09, 2021; Published: January 31, 2022

Abstract

Here we report a case of a 32-year-old male patient with bilateral haemorrhagic hypopyon as an unusual presenting feature of acute lymphoblastic leukaemia (ALL). Cytology of anterior chamber tap was suggestive of leukemic infiltration of the anterior chamber of the eyes, a sign of metastatic acute lymphoblastic leukemia. He was conservatively managed with topical steroids and cycloplegics. Patient was already initiated with chemotherapy under the care of an oncologist. A leukemic hypopyon is considered as an early sign of central nervous system involvement or systemic relapse. A finding of clinical significance, it should be immediately reported to the oncologist to urgently rule out CNS involvement and for aggressive management.

Keywords: Acute Lymphoblastic Leukaemia; Hypopyon; Acute Myeloblastic Leukemia

References

  1. Charif Chefchaouni M., et al. “Ophthalmic manifestations of acute leukemia”. Journal Français D'Ophtalmologie 25 (2002): 62-66.
  2. Ben-Simon GJ and Barequet IS. “Anterior uveitis as presenting sign of myeloproliferative disease”. Annals of Ophthalmology 35 (2003): 62-64.
  3. Sudharshan S., et al. “Bilateral Hypopyon as the Presenting Feature of Chronic Myeloid Leukemia”. Ocular Immunology and Inflammation 16 (2008): 244-246.
  4. Foster CS., et al. “Relapsing Acute Myeloid Leukemia Manifesting as Hypopyon Uveitis”. American Journal of Ophthalmology 119 (1995): 361-364.
  5. Yi DH., et al. “Acute unilateral leukemic hypopyon in an adult with relapsing acute lymphoblastic leukemia”. American Journal of Ophthalmology 139 (2005): 719-721.
  6. Ramsay A and Lightman S. “Hypopyon uveitis”. Survey of Ophthalmology 46 (2001): 1-18.
  7. Decker EB and Burnstine RA. “Leukemic relapse presenting as acute unilateral hypopyon in acute lymphocytic leukemia”. Annals of Ophthalmology 25 (1993): 346-349.

Citation

Citation: Sameer Iqbal., et al. “Bilateral Metastatic Acute Lymphoblastic Leukaemia Presenting as Hypopyon: A Case Report". Acta Scientific Ophthalmology 5.2 (2022): 29-31.

Copyright

Copyright: © 2022 Sameer Iqbal., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days
ISI- IF1.042
JCR- IF0.24

Indexed In




News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is December 25, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"

Contact US