Acta Scientific Ophthalmology (ISSN: 2582-3191)

Research Article Volume 4 Issue 12

Surgical Outcome of Trabeculectomy with Mitomycin - C Versus Trabeculectomy with Collagen Implant (Ologen), in Patients of Primary Open Angle Glaucoma: A Tertiary Centre Study

Mannnan R1*, Jolly FA2, Hossain F3, Bhowmik NC3 and Sayeed A4

1Glaucoma Specialist and Surgeon, Department of Ophthalmology, BIRDEM General Hospital, Dhaka, Bangladesh
2Associate Professor, Department of Ophthalmology, BIRDEM General Hospital, Dhaka, Bangladesh
3Assistant Professor, Department of Ophthalmology, BIRDEM General Hospital, Dhaka, Bangladesh
4Professor and Head, Department of Ophthalmology, BIRDEM General Hospital, Dhaka, Bangladesh

*Corresponding Author: Mannnan R, Glaucoma Specialist and Surgeon, Department of Ophthalmology, BIRDEM General Hospital, Dhaka, Bangladesh.

Received: November 01, 2021 ; Published: November 15, 2021

Abstract

Purpose: To compare the surgical outcome of trabeculectomy with Mitomycin-C (MMC) versus trabeculectomy with collagen(ologen) implant in medically uncontrolled, primary open angle glaucoma patients of Bangladeshi population.

Methods: A Quasi experimental study; conducted at BIRDEM General Hospital, Dhaka from July, 2015 to June, 2021 consisting of 36 eyes of 24 patients (> 40 years of age) of medically uncontrolled primary open angle glaucoma(POAG). Study patients were randomly distributed between two comparison groups: namely; GROUP 1: Trabeculectomy with Mitomycin-C and GROUP 2: trabeculectomy with collagen (Ologen) implant. All the surgeries were performed by single surgeon. Total six Post operative follow-up was done up to 12 months after surgery.At each visit, BCVA, IOP, any post operative complications of surgery as well as requirement of any anti-glaucoma drug or possible need of second surgical intervention for lowering IOP were noted.

Results: Mean IOP reduction after surgery was significantly less at all time points in both groups(p<0.05). Considering complete success criteria, survival probability in Ologen group was 94.8% at 6 months and 92.9% (95% CI: 59.1 - 99.0) at 12 months. The corresponding survival probability in MMC group was 95.2 and 93.8% (63.2 - 99.1) at 6 months and 12 months. There were no significant intra-operative complications in any of the eyes in either of the groups.

Conclusion: Surgical outcome of trabeculectomy with MMC was similar to that of trabeculectomy with Ologen implant.

Keywords: Trabeculectomy; Mitomycin-C; Collagen Implant; Surgical Outcome; Open Angle Glaucoma sss

References

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Citation

Citation: Mannnan R., et al. “Surgical Outcome of Trabeculectomy with Mitomycin - C Versus Trabeculectomy with Collagen Implant (Ologen), in Patients of Primary Open Angle Glaucoma: A Tertiary Centre Study".Acta Scientific Ophthalmology 4.12 (2021): 40-45.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days
ISI- IF1.042
JCR- IF0.24

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