Pachychoroid: A Phenotype Not Yet Understood
Manoj Soman*
Head, Vitreoretinal Services, Chaithanya Eye Hospital and Research Institute, Trivandrum, India
*Corresponding Author: Manoj Soman, Head, Vitreoretinal Services, Chaithanya Eye Hospital and Research Institute, Trivandrum, India.
Received:
September 23, 2021 ; Published: November 09, 2021
The term “pachychoroid” is a familiar term in retinal parlance and describes a unique disease phenotype characterized by functional and structural changes in the choroid. This phenotype is thought to play a key role in the pathogenesis of a spectrum of related retinal disorders, referred to as the “pachychoroid spectrum” [1]. The Pachychoroid spectrum predominantly include four disease conditions sharing common features - pachychoroid pigment epitheliopathy (PPE), central serous chorioretinopathy (CSCR), pachychoroid neovasculopathy (PNV), and polypoidal choroidal vasculopathy (PCV). These spectrums of diseases represent a distinct entity that has to be differentiated from typical age-related macular degeneration and other inflammatory and infilterative entities with thickened choroids. The common characteristics of this spectrum include the presence of pachyvessels represented by the dilated Hallers layer of the choroid, with overlying attenuation of the sattlers layer and choriocapillaris with or without increased thickness of the choroid [1]. The location and the overlying retinal manifestations may differ according to the clinical type of presentation.
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