Acta Scientific Ophthalmology (ISSN: 2582-3191)

Research Article Volume 4 Issue 11

Multifocal Visual Evoked Potential in Glaucoma

Mona Abdel Kader*

Professor, Department of Ophthalmology, Mansoura Ophthalmic Center, Egypt

*Corresponding Author: Mona Abdel Kader, Professor, Department of Ophthalmology, Mansoura Ophthalmic Center, Egypt.

Received: August 16, 2021; Published: October 25, 2021



Purpose: To determine the effect of glaucomatous damage on latency and amplitude of the multifocal visual evoked potential (MF-VEP), to compare latencies of conventional pattern visual evoked potential (C-VEP) and multifocal visual evoked potential and to compare diagnostic performance of MF-VEP and standard automated perimetry (SAP).

Participants: Thirty-five glaucomatous patients (70 eyes) and twenty- five normal controls (50 eyes) were enrolled in this study.

Methods: Monocular MF-VEP were recorded from glaucoma group and control group. Both eyes of (60) individuals were evaluated. Subjects ranged in age from 30 to 60 years in control and from 32 to 65years in glaucoma group. C- VEP and MF-VEP were obtained by using (Roland consult, Brandenburg, Germany) with four - electrode array. SAP visual field (Humphrey Field Analyzer, 640 Carl Zeiss, Co, Sanleandro, Calif) were obtained within days from VEP.

Results: Fifty-five eyes in glaucoma group had Humphrey field defect, of which 50 eyes (90%), Humphrey field defects were correlated with MF-VEP amplitude. Topographic location was well correlated with Humphrey field. Mean amplitude was significantly reduced in glaucoma eyes.

In 15 glaucoma patients with no scotoma by definition in the fellow eye, 13 had abnormal multifocal perimetry. In 55 glaucoma eyes with abnormal Humphrey visual field one had normal multifocal perimetry. Of 140 hemi field (35 glaucoma patients x two eyes x two hemi field), 110 hemi field showed significant clusters on HVF and 134 hemi field showed significant cluster on the MF-VEP. The amplitude of MF-VEP was correlated with Humphrey MD (r = 0,7, P = 0,000).

Conclusion: MF-VEP can assess the visual field and identify glaucomatous visual field defect. It may have the potential for identifying defects earlier than conventional perimetry. MF-VEP showed more abnormalities than SAP. However, although there were abnormalities detected by the MF- VEP that were missed by SAP, the reverse was true.

Keywords: Multifocal Visual Evoked Potential (MF-VEP); Conventional Pattern Visual Evoked Potential (C-VEP); Standard Automated Perimetry (SAP)



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Citation: Mona Abdel Kader. “Multifocal Visual Evoked Potential in Glaucoma".Acta Scientific Ophthalmology 4.11 (2021): 53-63.


Acceptance rate35%
Acceptance to publication20-30 days
ISI- IF1.042
JCR- IF0.24

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