Acta Scientific Ophthalmology (ISSN: 2582-3191)

Research Article Volume 4 Issue 9

Visual Outcome with Irrigation of the Interface in Small-Incision Lenticule Extraction

Andrew Yazji*, Joseph Ling, William F Wiley, Shamik Bafna, Ashraf Ahmad and Jeffrey Augustine

Cleveland Eye Clinic, Cleveland, Ohio, USA

*Corresponding Author: Andrew Yazji, Cleveland Eye Clinic, Cleveland, Ohio, USA.

Received: August 04, 2021; Published: August 26, 2021


Purpose: To compare the refractive and visual outcomes after Small-Incision Lenticule Extraction (SMILE) in patients receiving irrigation of the stromal interface versus no irrigation in the United States based on FDA-approved parameters.

Methods: In this US-based, single-center, consecutive, retrospective case series, patients undergoing SMILE received irrigation in one eye versus no irrigation in the other eye. Primary outcome measures included uncorrected visual acuity (UCVA) post-op day 1, post-op week 1, and post-op month 1, mean manifest refraction spherical equivalent (MRSE), and the number of patients within ±0.5 D and ±1.0 D of refractive target. Same-day post-op pachymetry and anterior-segment OCT were also obtained. Safety was assessed by noting the incidence of complications and need for additional surgery.

Results: 32 patients were included in the study, with 32 eyes in both the irrigated and non-irrigated groups. All patients were targeted for plano refraction. UCVA on POM1 was 0.0038 ± 0.164 D for irrigated eyes and -0.0154 ± 0.141 D for non-irrigated eyes (P = 0.40). The MRSE on POM1 was -0.232 ± 0.483 D for irrigated eyes and -0.274 ± 0.539 D for non-irrigated eyes. In the irrigated eyes group on POM1, 21 of 21 patients were within ±1.0 D of refractive target compared to 18 of 21 in the non-irrigated group. Adjusting for expected pachymetry, irrigated eyes had an average of 15.406 ± 0.347 microns thicker post-operative pachymetry readings compared to the non-irrigated eyes (P = 0.006).

Conclusion: Irrigated eyes had better UCVA, lower MRSE, and deviated less from their refractive target compared to non-irrigated eyes. Irrigated eyes had a significant increase in corneal pachymetry measured immediately postoperatively compared to non-irrigated eyes, however its effect on visual outcome was not significant.

Keywords: SMILE; Refractive Surgery; Ophthalmic Surgery


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Citation: Andrew Yazji., et al. “Visual Outcome with Irrigation of the Interface in Small-Incision Lenticule Extraction".Acta Scientific Ophthalmology 4.9 (2021): 59-62.


Copyright: © 2021 Andrew Yazji., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate35%
Acceptance to publication20-30 days
ISI- IF1.042
JCR- IF0.24

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