Acta Scientific Ophthalmology (ISSN: 2582-3191)

Case Report Volume 4 Issue 5

Juvenile Open Angle Glaucoma: A Report of Three Sons in One Family

Said M Shalaby, Wesam Shamseldin Shalaby* and Ahmed F Elmaria

Ophthalmology Department, Tanta Medical School, Tanta University, Egypt

*Corresponding Author: Wesam Shamseldin Shalaby, Ophthalmology Department, Tanta Medical School, Tanta University, Egypt.

Received: March 18, 2021; Published: April 01, 2021

×

Abstract

A male child aged 16 years old diagnosed with bilateral juvenile open angle glaucoma (JOAG) underwent trabeculectomy with mitomycin C (MMC) in both eyes. For 5 years follow-up, no complications were recorded, and the intraocular pressure (IOP) was well controlled. Family screening was done and revealed JOAG in his brother, 13 years old, and his sister, 9 years old. Both underwent trabeculectomy with MMC. Ologen implant was intraoperatively added in the younger sister. Examination of the parents revealed that their mother, 45 years old, had mild primary open angle glaucoma and medical treatment was prescribed for her with good IOP control, stable perimetry and retinal nerve fiber layer thickness for 4 years follow-up.

Keywords: Juvenile Open Angle Glaucoma; Mitomycin C; Ologen; Trabeculectomy

×

References

  1. Johnson AT., et al. “Clinical features and linkage analysis of a family with autosomal dominant juvenile glaucoma”. Ophthalmology 4 (1993): 524-529.
  2. Park SC and Kee C. “Large diurnal variation of intraocular pressure despite maximal medical treatment in juvenile open angle glaucoma”. Journal of Glaucoma 1 (2007): 164-168.
  3. Kwun Y., et al. “Clinical Characteristics of Juvenile-onset Open Angle Glaucoma”. Korean Journal of Ophthalmology 2 (2016): 127-133.
  4. Khan AO. “Genetics of primary glaucoma”. Current Opinion in Ophthalmology 5 (2011): 347-355.
  5. Yen YC., et al. “Identification of mutations in the myocilin (MYOC) gene in Taiwanese patients with juvenile-onset open-angle glaucoma”. Molecular Vision 13 (2007): 1627-1634.
  6. Aponte EP., et al. “Incidence and clinical characteristics of childhood glaucoma: a population-based study”. Archives of Ophthalmology 4 (2010): 478-482.
  7. Wiggs JL., et al. “Prevalence of mutations in TIGR/Myocilin in patients with adult and juvenile primary open-angle glaucoma”. American Journal of Human Genetics 5 (1998): 1549-1552.
  8. Pasutto F., et al. “Heterozygous NTF4 mutations impairing neurotrophin-4 signaling in patients with primary open-angle glaucoma”. American Journal of Human Genetics 4 (2009): 447-456.
  9. Ang GS., et al. “Postoperative infection in penetrating versus non-penetrating glaucoma surgery”. British Journal of Ophthalmology 12 (2010): 1571-1576.
  10. Arora S., et al. “Efficacy and safety of ab interno trabeculectomy in juvenile open-angle glaucoma”. The Canadian Journal of Ophthalmology 5 (2018): 482-486.
×

Citation

Citation: Wesam Shamseldin Shalaby., et al. “Juvenile Open Angle Glaucoma: A Report of Three Sons in One Family".Acta Scientific Ophthalmology 4.5 (2021):12-14.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days
ISI- IF1.042
JCR- IF0.24

Indexed In




News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is July 10, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US