Acta Scientific Ophthalmology (ISSN: 2582-3191)

Research Article Volume 4 Issue 4

Corneal Calcium Deposits: Phosphate ROL in Eye Drops

D´Alessandro Leonardo P1*, Mariani Licina2 and Picco Melisa2

1Centro De Los Sentidos, Argentina
2Fundación Oftalmológica Argentina Jorge Malbran, Argentina

*Corresponding Author: D´Alessandro Leonardo P, Centro De Los Sentidos, Argentina.

Received: August 27,2020; Published: March 10, 2021



Objective: To bring awareness to the ophthalmologist about the state of the discussion in relation to the issue regarding the phosphate content in the collyriums for ophthalmic use. In order to inform professionals so they could make an appropriate selection of the medicine to be prescribed.

Materials and Methods: Review of the composition of the eye drops market in the country and registry of the phosphate levels.

Data was retrieved from information provided by pharmaceutical companies and by Administración de Medicamentos, Alimentos y Tecnología Médica (ANMAT) [National Administration for Drugs, Food and Medical Technology] from the Argentine Republic.

Results: Through the analysis, it was seen that most collyrium which are marketed in our country have phosphate concentrations higher than the physiological lacrimal concentration (0.4 - 1.45 mmol/L).

Conclusion: In patients who present an alteration of the surface and/or ocular inflammation, the administration of drops with high levels of phosphate is implicated in the generation of calcium precipitation phenomena at the corneal level. The selection of eye drops which do not contain phosphates, or which contains them at physiological levels, might have a beneficial impact on the management of the patient.

Keywords: Eye Drops; Corneal Calcifications; ANMAT



Citation: D´Alessandro Leonardo P., et al. “Corneal Calcium Deposits: Phosphate ROL in Eye Drops". Acta Scientific Paediatrics 4.4 (2021): 66-72.


Acceptance rate35%
Acceptance to publication20-30 days
ISI- IF1.042
JCR- IF0.24

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