Acta Scientific Ophthalmology (ISSN: 2582-3191)

Research Article Volume 4 Issue 3

Comparative Evaluation of 0.1% and 0.01% Topical Atropine Eyedrops in Myopic Children

Sonam Juneja1, Anand Aggarwal1,2*, Prempal Kaur1, Karamjit Singh1, Harvinder Nagpal2, Chiman Lal2 and Konica Singla1

11Government Medical College, Amritsar, India
2Government Medical College, Patiala, India

*Corresponding Author: Anand Aggarwal, Government Medical College, Amritsar and Government Medical College, Patiala, India.

Received: January 14, 2021; Published: February 08, 2021



Aim: To compare effects of 0.1% and 0.01% topical atropine eyedrops in myopic children.

Methods : This prospective randomized study was conducted on 80 eyes of 40 myopic children irrespective of age, type of myopia and amount of spherical equivalent correction. 40 eyes were subjected to 0.1% (Group A) and 40 to 0.01% topical atropine once at night (Group B). Follow-up was done at 3 months,6 months, 1 and 2 years. The effect of atropine on mean change in spherical equivalent, axial length, pupil diameter, keratometry and intra ocular pressure was recorded and compared between two groups. Any adverse effect as well as drop in near vision due to atropine was also noted.

Results: Mean age group studied in two groups was 10.5 years (range 5-13 years). The mean change in spherical equivalent after 2 years of atropine therapy was -0.35 ± 0.93 D in group A and -0.04 ± 0.57 D in group B (p < 0.05), the mean change in axial length was 0.27 ± 0.38 mm in group A and 0.05 ± 0.30 mm in group B (p > 0.05) and the mean change in pupil diameter was 1.05 ± 0.36 in group A and 0.84 ± 0.14 in group B (p < 0.05). 11 (55%) patients of group A and 6 (30%) patients of group B had difficulty while reading. However no statistical significant change was found in intraocular pressure and keratometric readings.

Conclusion: Both 0.1% and 0.01% topical atropine have comparable role in stabilization of myopia over 2 years. However, fewer visual side effects were noted with 0.01% atropine vs 0.1% atropine.

Keywords: Atropine; Children; Myopia; Spherical Equivalent



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Citation: Anand Aggarwal. “Comparative Evaluation of 0.1% and 0.01% Topical Atropine Eyedrops in Myopic Children".Acta Scientific Ophthalmology 4.3 (2021): 03-09.


Acceptance rate35%
Acceptance to publication20-30 days
ISI- IF1.042
JCR- IF0.24

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