Abstract

Objective: To evaluate and compare meibomian gland dysfunction in diabetic and non-diabetic patients.

Design: This was a prospective study conducted on 400 eyes of 100 diabetic patients (group 1) and 100 non- diabetic patients (group 2) who presented to out-patient department and were diagnosed with meibomian gland dysfunction from January 2019 to January 2020.Meibomain gland dysfunction was evaluated by noting the symptoms, determining the grade of meibomian gland expressibility and meibum quality under slit lamp and ocular surface staining. Clinical staging of meibomian gland dysfunction was obtained and the results were compared in both the groups.

Results: The age range of patients in both the groups was 40 to 65 years. The mean blood sugar level in group 1 was 225.16 ± 53.29 (mg/dl) while in group 2 was 99.64 ± 8.58 (mg/dl). Burning sensation in the eyes was found to be the most common symptom in both the groups. The severity of symptoms was significantly more among the diabetic group compared to non-diabetic group (p = 0.001). Meibum quality and expressibility grading was significantly greater in group 1 compared to group 2 (p < 0.05). There was statistically significant increase in ocular surface staining in group 1 compared to group 2 (p < 0.001).Clinical staging of meibomian gland dysfunction was obtained which showed significantly high stage (stage 3,4) meibomian gland dysfunction in diabetic patients compared to non-diabetic patients (p < 0.001).

Conclusion: Our data suggests that meibomian gland dysfunction in diabetic patients is more severe compared to non-diabetic patients.

Keywords: Meibomian Gland; Meibum; Meibomian Gland Dysfunction; Diabetes

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Citation

Citation: Karamjit Singh. “Comparative Evaluation of Meibomian Gland Dysfunction in Diabetic and Non-Diabetic Patients at a Tertiary Care Centre in Punjab".Acta Scientific Ophthalmology 4.2 (2021): 36-42.

Copyright

Copyright: © 2021 Karamjit Singh This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.