Acta Scientific Ophthalmology (ISSN: 2582-3191)

Research Article Volume 4 Issue 1

Effect of Refractive Error on Visual Evoked Potential in Myopic Males and Females

Chanda Kumari Gupta1*, Smriti Ranabhat1 and Rahul Roy2

1Nethradhama School of Optometry, Bangalore, India
2Assitant Professor, Nethradhama School of Optometry, Bangalore, India

*Corresponding Author: Chanda kumari Gupta, Nethradhama School of Optometry, Bangalore, India.

Received: December 08, 2020; Published: December 29, 2020



Introduction: Visual Evoked Potentials are summated electrical signals generated by occipital regions of cortex in response to visual stimuli and recorded from human scalp. Visual evoked potential measures the conduction time of neuronal activity from retina to occipital cortex, the measure of integrity and function of visual pathway. The amplitude and latency of visual evoked potential are affected by variety of physiological factors like refractive errors, age, gender, eye movement and also the techniques like check size, color, distance to pattern etc. To find out the effect of myopia on visual evoked potential, this study was conducted on males and females.

Method: 50 controls [25 males, 25 females] and 50 myopic [25males, 25 females] aged between 18-30 years with refractive error in range of -0.5D to -5.00 D were participated with cylindrical component less than -1.00 D with no significant difference in spherical equivalent between the eyes. VEP was measured using full field pattern reversal checkerboard pattern as stimuli and refractive error as measured both objectively and subjectively.

Results: Statistical analysis showed significant prolongation of P100 latency in myopic subjects along with significant reduction in P100 amplitude. When compared according to gender P100 latency significantly increased and the amplitude decrease was also found significant. When Spherical equivalent was co related with VEP latency and amplitude in the whole group, VEP latency showed negative correlation and weak positive correlation for VEP amplitude which was insignificant. When co-relating in males, we found negative correlation for latency and insignificant amplitude whereas in females, latency showed negative correlation with significant amplitude.

Conclusion: As significant changes in VEP was seen in case of myopia in both genders, refractive errors should also be kept in mind while performing VEP for optic pathway evaluations in order to minimize false positive results.

Keywords: VEP - Pattern Reversal; Amplitude; Latency; Myopia; BMI



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Citation: Chanda Kumari Gupta., et al. “Effect of Refractive Error on Visual Evoked Potential in Myopic Males and Females".Acta Scientific Ophthalmology 4.1 (2021): 22-26.


Acceptance rate35%
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ISI- IF1.042
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