Acta Scientific Ophthalmology (ASOP)

Case Report Volume 3 Issue 9

Endogenous Endophthalmitis in a Two-Week-Old Neonate with Hypofibrinogenemia

Ahlam Al-Hamhami1, Anuradha Ganesh2*, Maha Mameesh1,3, Sana Al-Zuhaibi1, Sameer Raniga S4, Yasser Wali5,6 and Abdullah Al-Mujaini1

1Sultan Qaboos University Hospital, Muscat, Sultanate of Oman
2Nizwa Hospital, Sultanate of Oman
3Faculty of Medicine, Alexandria University, Alexandria, Egypt
4Department of Radiology, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman
5Department of Child Health, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman
6Department of Pediatrics, Faculty of Medicine, Alexandria University, Alexandria, Egypt

*Corresponding Author: Anuradha Ganesh, Senior Consultant, Departments of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman.

Received: August 14, 2020; Published: August 25, 2020

×

Abstract

We report a two-week-old neonate with congenital hypofibrinogenemia and neonatal sepsis who developed left endogenous endophthalmitis. Gram positive bacillus Rothia dentocariosa and Gram negative bacillus E. coli were isolated from blood culture. Despite early initiation of both topical and systemic antibiotic therapy the baby had a deteriorating course and the eye was eviscerated.

Keywords: Hypofibrinogenemia; Septicemia; Endogenous Endophthalmitis; R. dentocariosa; E. coli; Evisceration

×

References

  1. López Sastre JB., et al. “Neonatal invasive Candidiasis: A Prospective Multicenter Study of 118 Cases”. The American Journal of Perinatology 20 (2003): 153-163.
  2. Moshfeghi AA., et al. “Declining incidence of neonatal endophthalmitis in the United States”. American Journal of Ophthalmology 151 (2011): 59‐65.
  3. Aziz HA., et al. “Intraocular infections in the neonatal intensive care unit case series”. Clinical Ophthalmology 6 (2012): 733-737.
  4. De Moerloose P., et al. “Congenital fibrinogen disorders: an update”. Seminars in Thrombosis and Hemostasis 39 (2013): 585-595. 
  5. Jackson TL., et al. “Endogenous Bacterial Endophthalmitis: A 17-year Prospective Series and Review of 267 Reported Cases”. Survey of Ophthalmology 48 (2003): 403-423.
  6. Basu S., et al. “Neonatal Endogenous Endophthalmitis: A Report of Six Cases”. Pediatrics 131 (2013): 1292-1297. 
  7. Chaudhry IA., et al. “Pediatric endogenous bacterial endophthalmitis: case report and review of the literature”. Journal of AAPOS 10 (2006): 491-493.
  8. MacKinnon MM., et al. “A case of Rothia dentocariosa endophthalmitis”. European Journal of Clinical Microbiology and Infectious Diseases 20 (2001): 756-757.
  9. Partner AM., et al. “Rothia genus endophthalmitist following penetrating injury in a child”. Eye 20 (2006): 502-503.
  10. Pathengay A., et al. “Spontaneous bilateral subhyaloid hemorrhage in congenital hypofibrinogenemia”. Retinal Cases and Brief Reports 5 (2011): 160-162. 
  11. Jalali S., et al. “Treatment outcomes and clinicomicrobiological characteristics of a protocol-based approach for neonatal endogenous endophthalmitis”. European Journal of Ophthalmology 24 (2014): 424‐436.
  12. Greenwald MJ., et al. “Metastatic Bacterial Endophthalmitis: A Contemporary Reappraisal”. Survey of Ophthalmology 31 (1986): 81-101.
  13. Khan S., et al. “Pediatric infectious endophthalmitis: a review”. The Journal of Pediatric Ophthalmology and Strabismus 51 (2014): 140-153. 
  14. Hui JI. “Outcomes of orbital implants after evisceration and enucleation in patient with endophthalmitis”. Current Opinion in Ophthalmology 21 (2010): 375-379.
  15. Balaskas K and Potamitou D. “Endogenous endophthalmitis secondary to bacterial meningitis from Neisseria Meningitidis: a case report and review of the literature”. Cases Journal 2 (2009): 149.
×

Citation

Citation: Anuradha Ganesh., et al. “Endogenous Endophthalmitis in a Two-Week-Old Neonate with Hypofibrinogenemia”.Acta Scientific Ophthalmology 3.9 (2020): 40-44.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days
ISI- IF1.042
JCR- IF0.24

Indexed In




News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is December 25, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"

Contact US