Mingxin Liu1, Fangjian Xing1*, Chenliang Chang2, Jonghwan Lee3,4, Caojin Yuan1, Shouping Nie1, Shaotong Feng1
1Key Laboratory for Opto-Electronic Technology of Jiangsu Province, Nanjing Normal University, Nanjing, China
2Department of Bioengineering, University of California, Los Angeles, Los Angeles, USA
3Center for Biomedical Engineering, School of Engineering, Brown University, Providence, Rhode Island, USA
4Carney Institute for Brain Science, Brown University, Providence, USA
*Corresponding Author: Fangjian Xing, Key Laboratory for Opto-Electronic Technology of Jiangsu Province, Nanjing Normal University, Nanjing, China.
Received: March 05, 2020; Published: March 16, 2020
A Fast Monte Carlo simulation based on the spectroscopic optical coherence tomography (SOCT) simulated the back reflection of millions of photons in tissues within tens of minutes. Combined with the short time Fourier transform, the reflection intensity at sixteen wavelengths in visible waveband was achieved. The blood oxygen saturation (SO2) was nonlinear fitted through the different absorption coefficients of the oxyhemoglobin and de-oxyhemoglobin at sixteen wavelengths. We designed a model to simulate human retinal blood vessels and measure retinal oximetry. The results showed that the simulation results were consistent with the theory.
Keywords: Spectroscopic Optical Coherence Tomography (SOCT); Fast Monte Carlo Simulation; Fiber Coupler
Citation: Fangjian Xing., et al. Assessment of Blood Oxygen Saturation by Visible Optical Coherence Tomography Based on Fast Monte Carlo Simulation Acta Scientific Ophthalmology 3.4 (2020): 03-07.
Copyright: © 2020 Fangjian Xing., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.