Various Types of Coating of the Mechanical Circulation Support Pump Impact on Hemolytic and Homeostatic Blood Parameters

KO Golovin^1,2, AM Golovin² and RI Aizman^1,3*

¹Novosibirsk State Pedagogical University, Novosibirsk, 630126, Vilyuiskaya Str., 28, Russia
²NPK "IMPULSE-Project", Novosibirsk, Russian Federation 630073, Novosibirsk, Gorsky Microdistrict, 10, Russia
³Novosibirsk Scientific Research Institute of Hygiene of Rospotrebnadzor, 630108, Novosibirsk, Parkhomenko Str., 7, Russia

*Corresponding Author: RI Aizman, Novosibirsk State Pedagogical University, Novosibirsk, 630126, Vilyuiskaya Str., 28, Russia.

Received: February 17, 2025; Published: September 11, 2025

Abstract

Mechanical circulatory support can lead to hemolysis, thrombosis, bleeding, and other complications. The aim of the study was to determine the degree of influence of various types of coating of the disk pump for mechanical circulatory support on hemolytic blood parameters.

Materials and Methods: In vitro studies were conducted on a specialized device that simulated a large circle of blood circulation. Human donated blood was used for the study.

Results and Discussion: It was found that using an uncoated and diamond-coated disc pump, an increase in the level of FreeHb in blood plasma was noted from a baseline value of 0.01 g/l to 0.12 g/l and from 0.02 to 0.09 g/l, respectively. In studies, where a disk pump with a surface treated by electron beam with a silicon-carbon coated was used, the concentration of FreeHb in blood plasma remained at the background level.

Conclusion: It is shown that a disk pump with a surface treated by electron beam with a silicon-carbon coated caused the smallest changes of the studied blood parameters.

 Keywords: Disc Pump; Coating; FreeHb; Hemolysis

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Citation

Citation: RI Aizman., et al. “Various Types of Coating of the Mechanical Circulation Support Pump Impact on Hemolytic and Homeostatic Blood Parameters ”.Acta Scientific Medical Sciences 9.10 (2025): 39-44.

Copyright

Copyright: © 2025 RI Aizman., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.