Abdulrahman Bin Matar Al-Mughari¹*, Walid Mishaal Madaj Al-Maghibi², Mohammad Nasser AL Qahtani¹, Ahmad Ali Al-Ghamdi¹ and Ahmed Abdulrahman Ibn Omayrah¹

¹Medical Laboratory Specialist, Prince Sultan Military Medical City, Riyadh, Saudi Arabia
²Laboratory Technician, Prince Sultan Military City, Riyadh, Saudi Arabia

*Corresponding Author: Abdulrahman Bin Matar Al-Mughari, Medical Laboratory Specialist, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.

Received: February 13, 2025; Published: February 28, 2025

Abstract

Background: Arterial blood gas measurement is now the gold standard for assessing ventilatory dysfunction, metabolic abnormalities, and progress. There is ongoing discussion on the efficacy of venous blood gas in treating COPD patients. This study set out to systematically evaluate the clinical usefulness of venous blood gas in the diagnosis of COPD.

Method: The investigation was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. Keywords pertaining to blood gas analysis in COPD patients were used to search databases such as Medline, Google Scholar, and Scopus. Articles published between 2011 and 2024 were considered. Among the search terms are COPD, blood gas analysis, emergency, acute exacerbation, case-control study, cohort study, and risk factors.

Result and Conclusion: A total of 667 patients from 5 publications were included in this study. Although arterial and venous blood gases have a broad connection, there are slight differences in pH, pCO2, and HCO3. Four studies found a significant level of agreement between ABG and VBG values for pH and pCO2. One research emphasized how the importance to analyze samples promptly and how air pollution and sample delay affect these results, particularly pH and PO2. The ABG remains the gold standard of treatment in many clinical settings. However, VBG is increasingly being used to treat respiratory failure in patients with an acute exacerbation of COPD.

 Keywords: Venous Blood Gases; Arterial Blood Gases; Chronic Obstructive Pulmonary Disease

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Citation

Citation: Abdulrahman Bin Matar Al-Mughari., et al. “Role of Venous Blood Gases in the Diagnosis of Chronic Obstructive Pulmonary Disease Exacerbation; Systematic Review”.Acta Scientific Medical Sciences 9.3 (2025): 106-111.

Copyright

Copyright: © 2025 Abdulrahman Bin Matar Al-Mughari., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.