Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Case Report Volume 9 Issue 2

Male Infertility in Duodenitis due to Celiac Disease

Hugh James Freeman*

Professor, Department of Medicine (Gastroenterology), University of British Columbia, Vancouver, BC, Canada

*Corresponding Author: Hugh James Freeman, Professor, Department of Medicine (Gastroenterology), University of British Columbia, Vancouver, BC, Canada.

Received: December 19, 2024; Published: January 21, 2025

Abstract

Patients with celiac disease may present or develop extra-intestinal changes, including infertility, during the clinical course. This appears to be more common in female patients. A 36 yr-old male was investigated for infertility. In this case, diagnosis was initially delayed because of misinterpretation of the pathological label of “duodenitis”. Celiac disease was eventually diagnosed after his clinical, laboratory and histological response to a strict gluten-free diet. Three years after his initial diagnosis of celiac disease, testicular atrophy with altered sperm analyses was defined. Male infertility may occur in celiac disease, even after resolution of biopsy and nutritional changes with a gluten-free diet.

Keywords: Male Infertility; Celiac Disease; Primary and Secondary Infertility; Testicular Atrophy; Duodenitis

References

  1. Freeman HJ. “Celiac disease: a disorder emerging from antiquity, its evolving classification and risk, and potential new treatment paradigms”. Gut Liver 9 (2015): 113-117.
  2. Gujral N., et al. “Celiac disease: prevalence, diagnosis, pathogenesis and treatment”. World Journal of Gastroenterology 18 (2012): 6036-6059.
  3. Freeman HJ. “Reproductive changes associated with celiac disease”. World Journal of Gastroenterology 16 (2010): 5810-5814.
  4. Freeman HJ. “Detection of adult celiac disease with duodenal screening biopsies over a 30-year period”. Canadian Journal of Gastroenterology 27 (2013): 405-408.
  5. Gillett PM., et al. “High prevalence of celiac disease in patients with type 1 diabetes detected by antibodies to endomysium and tissue transglutaminase”. Canadian Journal of Gastroenterology 15 (2001): 297-301.
  6. Freeman HJ. “Pancreatic exocrine and endocrine changes in celiac disease”. World Journal of Gastroenterology 13 (2007): 6344-6346.
  7. Freeman HJ. “Endocrine manifestations in celiac disease”. World Journal of Gastroenterology 22 (2016): 8472-8479.
  8. Freeman HJ. “Autoimmune thyroid disease with hypothyroidism in adult celiac disease”. International Journal of Celiac Disease 4 (2016): 121-123.
  9. Freeman HJ. “Autoimmune adrenal insufficiency in celiac disease”. International Journal of Celiac Disease 4 (2016): 84-86.
  10. Freeman HJ. “Primary hyperparathyroidism in biopsy-defined adult celiac disease”. Acta Scientific Gastrointestinal Disorders 7 (2024): 10-12.
  11. Freeman HJ. “Infertility and ovarian failure in celiac disease”. World Journal of Obstetrics and Gynecology 4 (2015): 72-76.
  12. Freeman HJ. “Mucosal recovery and mucosal healing in biopsy-defined celiac disease”. International Journal of Celiac Disease 5 (2017): 10-13.
  13. Freeman HJ. “Sprue-like small intestinal disease 2024”. International Journal of Celiac Disease 12 (2024).
  14. Freeman HJ. “Pearls and pitfalls in diagnosis of adult celiac disease”. Canadian Journal of Gastroenterology 22 (2008): 273-280.

Citation

Citation: Hugh James Freeman. “Male Infertility in Duodenitis due to Celiac Disease”.Acta Scientific Medical Sciences 9.2 (2025): 83-85.

Copyright

Copyright: © 2025 Hugh James Freeman. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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