Dr. Anusha Sunder*

Doctorate in Life Science/Human Nutrition, Accredited Certification in Nutrigenetics; Lead Scientist and Nutrigenetic Expert, Xcode Life Sciences, Pvt. Ltd. Chennai, India

*Corresponding Author: Dr. Anusha Sunder, Doctorate in Life Science/Human Nutrition, Accredited Certification in Nutrigenetics; Lead Scientist and Nutrigenetic Expert, Xcode Life Sciences, Pvt. Ltd. Chennai, India.

Received: May 06, 2024; Published: June 28, 2024

Abstract

One of the main threats of competitive sports is painful injuries. Athletes’ joints are vulnerable and they are exposed to frequent injuries. Genetic variations contributing to the onset of musculoskeletal injuries, particularly in tendon and ligament tissues, have been identified and these impact the athletic performance [1]. For instance, in tendons and ligaments, genes encode production and remodelling of collagen fibers (COL1A1, COL12A1 and COL5A1, MMP3), modulate their elastic and biomechanical properties (TNC, ELN), as well as influence their growth differentiation factors (GDF5, IGF2). Thus their unfavourable expressions can pose a risk for tendinopathy. Exercise/sports activity triggers a local, systemic inflammatory cascade with a release of both pro- and anti-inflammatory cytokines (such as TNFα, IL-6, CRP). The balance between them decides the recovery pace for a sport-induced injury. Genes determine the degree of body’s response to enhance repair and recovery processes after exercising. And injury recovery capacity is decisive in determining the amount of rest period required between exercises. Thus genetic variations fundamentally influence the susceptibility for sport-related injuries and the innate recovery potential. And this insight is much needed for implementing preventive and coping strategies [2]. Among other options used by trainers, physicians and athletes, nutritional support tailor-made to suit the genetic makeup may help enhance recovery.

 Keywords: Gene; Genetic Variations; Mutation; Allele; Injury-Susceptible Allele; Single Nucleotide Polymorphism/SNP; Flexibility; Tendinopathy; Gene-Specific Nutrients

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Citation

Citation: Dr. Anusha Sunder “Genes Can Express Injury Propensity and Recovery Pace in Sports”.Acta Scientific Medical Sciences 8.7 (2024): 257-265.

Copyright

Copyright: © 2024 Dr. Anusha Sunder This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.