Mehtap Tınazli and Gaukhar Bakhtiyarova*

Near East University Hospital, School of Medicine, Department of Endocrinology and Internal Medicine, Turkish Republic of Northern Cyprus, Nicosia

*Corresponding Author: Gaukhar Bakhtiyarova, Near East University Hospital, School of Medicine, Department of Endocrinology and Internal Medicine, Turkish Republic of Northern Cyprus, Nicosia.

Received: July 17, 2023; Published: September 29, 2023

Abstract

As we all know, a new coronavirus was detected in Wuhan, China in December 2019. Patients infected with 2019-nCoV, later named SARS-Cov-2, were reported to have fever, cough, fatigue, and shortness of breath. The novel coronavirus severe acute respiratory syndrome (SARS-CoV-2) has rapidly progressed from an epidemic to a global pandemic, with new variants rapidly emerging. Because of the highly contagious and deadly nature of the virus, finding effective treatments was a top priority and a global pandemic was declared by the World Health Organization (WHO) on 11 March.

Vitamin D is an immunomodulatory hormone with proven efficacy against various upper respiratory tract infections. Vitamin D may be protective against acute respiratory infections as it modulates the inflammatory cytokine response of respiratory epithelial cells and macrophages, suppressing CS and other manifestations seen in SARS-Cov-2. Therefore, it is recommended as one of the treatment options in SARS-CoV-2 infection. In 20 European countries, low vitamin D levels were observed in cases of COVID-19 with a higher incidence of mortality, increased risk of death during disease severity, need for intensive care and even Covid-19 infection contributing to ARDS or fulminant myocarditis.

In this review, it was aimed to investigate the role of vitamin D in the prevention and treatment of the severe course of COVID-19. While there have been some conflicting results reported, the consensus is that vitamin D has a number of immunomodulatory effects that may be beneficial in the context of COVID-19, and that low levels of vitamin D can cause and potentially contribute to dysfunction of significant antimicrobial effects.

In addition, some studies show that the effects of vitamin D deficiency can be alleviated by supplementation, and vitamin D supplementation is recommended in Covid-19 infection because it is inexpensive, easy to use and safe.

 Keywords: Coronavirus; SARS-Co-V-19; Vitamin D; Immune System; COVID-19; Infection; Review

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Citation

Citation: Mehtap Tınazli and Gaukhar Bakhtiyarova. “Relationship between Vitamin D Deficiency and Covid-19”.Acta Scientific Medical Sciences 7.10 (2023): 45-52.

Copyright

Copyright: © 2023 Mehtap Tınazli and Gaukhar Bakhtiyarova. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.