Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 7 Issue 9

Invasive Fungal Infections in A Teritiary ICU in Hyderabad

Sudeep Sirga1, K Hima Bindu2*, Ratnamani MS3, Jamadanda Prathiba4, Nagaraju Gorla5, Chandana Lakkoju6, Sai Druthi Pasupuleti6 and Subbareddy Kesavarapu7

1Senior Consultant, Department of Critical Care, Apollo Hospitals, Jubilee Hills, Hyderabad, India
2Consultant, Department of Critical Care, Apollo Hospitals, Jubilee Hills, Hyderabad, India
3Senior Consultant and HOD, Department of Microbiology, Hyderabad, India
4Senior Consultant, Department of Microbiology, Hyderabad, India
5Senior Consultant, Department of Critical Care, Apollo Hospitals, Jubilee Hills, Hyderabad, India
6Registrar, Department of Critical Care, Apollo Hospitals, Jubilee Hills, Hyderabad, India
7Senior Consultant and HOD, Department of Critical Care, Apollo Hospitals, Jubilee Hills, Hyderabad, India

*Corresponding Author: K Hima Bindu, Consultant, Department of Critical Care, Apollo Hospitals, Jubilee Hills, Hyderabad, India.

Received: August 22, 2023; Published: August 31, 2023

Abstract

The COVID-19 pandemic has caused more than 500 million cases and 6 million fatalities globally, with India particularly heavily struck by the second wave. This has significantly increased the prevalence of invasive fungal diseases, such as COVID-19-associated pulmonary mucormycosis (CAPM) and COVID-associated pulmonary aspergillosis.
A retrospective study was conducted to examine the incidence of IFI in a tertiary care ICU in South India during the pandemic. Data was collected from medical records of patients with documented positive fungal cultures. Results showed that the incidence of COVID-19-associated pulmonary mucormycosis (CAPM) and COVID-associated pulmonary aspergillosis had increased significantly.
The study examined 41 medical and surgical patients admitted to ICU in a tertiary care hospital in Hyderabad from January 2020 – December 2022 with documented culture-positive invasive fungal infections. The most common source of fungal infection was from lung, followed by the maxillary sinus tissue, nasal cavity, peritoneal fluid, Frontal sinus tissue, and urine. Fungal cultures were positive in 36 cases (87.8%) and negative in 1, and not done in 4 patients. Rhizopus was the first most frequently identified fungus, followed by Aspergillus flavus (26.8%), Aspergillus fumigatus (7.3%), Aspergillus niger (7.3%), Candida tropicalis and albicans (2.4%), Candida parapsilosis (7.3%), Mucormycosis (2.4%), and seedosporium (2.4%).

Keywords: Invasive Fungal Infections; COVID 19; Mucor; Aspergillus; Critical Care; Candida

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Citation

Citation: K Hima Bindu., et al. “Invasive Fungal Infections in A Teritiary ICU in Hyderabad". Acta Scientific Medical Sciences 7.9 (2022): 183-191.

Copyright

Copyright: © 2022 K Hima Bindu., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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