Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 7 Issue 8

Leishmaniasis in the Kingdom of Saudi Arabia: Epidemiological Trends from 2019 to 2021: A Retrospective Study

Mohammed Othman Alkurbi1, Raafat Abdel Moneim Hassanein1,2* and Mohammed Othman Alkurbi1

1Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Saudi Arabia
2Department of Zoonoses, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt

*Corresponding Author: Raafat Abdel Moneim Hassanein, Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Saudi Arabia.

Received: August 08, 2023; Published: August 25, 2023

Abstract

Background: Leishmaniasis is a vector-borne disease caused by different species belonging to the genus Leishmania. Leishmaniasis is endemic in Saudi Arabia with cases reported in many regions. This retrospective study aimed to determine the epidemiological trends of leishmaniasis in the different regions of the Kingdom of Saudi Arabia (KSA) from 2019-2021.

Methods: The analyzed data were based on surveillance and registry database of the Saudi Ministry of Health and included the reported regions, patients’ age groups, gender and the leishmaniasis clinical forms, their annual and month-by-month recorded patterns. Overall, a total of 2763 confirmed cases of cutaneous leishmaniasis (CL) were reported in KSA; divided as 1096, 1067 and 600 cases in 2019, 2020 and 2021, respectively. In addition, two visceral leishmaniasis (VL) patients only were reported during 2021G, one case recorded in Saudi patient and another one in non-Saudi.

Results: The highest number of the cutaneous leishmaniasis (CL) were from Medina region, western region of KSA (N = 655/2763, 23.7%) from 2019 to 2021; (N = 246/2763, 8.9%) in 2019; (N = 262/2763, 9.48%) in 2020 and (N = 147/2763, 5.32%) in 2021, while the lowest number was reported in Makkah region (N = 1 case in 2019). The cutaneous leishmaniasis (CL) were 49.65% Saudis and 50.34% non-Saudi expatriates with a ratio around 1.0: 1.02. The cutaneous leishmaniasis (CL) re-categorized in 2020 to 2021G as (1344/1667; 80.62%) males and (323/1667; 19.37%) females with a ratio of 4.0:1.0. In relation to patients’ age group, the majority of the reported cutaneous leishmaniasis cases were in 15-˂45 years (1072/1667; 64.3%) and the lowest number (13/1667; 0.77%) was in age group of <1 year during the period of 2020 to 2021.

Conclusion: Taken together, the present findings indicate the persistency of leishmaniasis endemicity, particularly cutaneous leishmaniasis, in KSA and Medina region is the most affected one. Thus, sustainable monitoring of leishmaniasis and improving its control measures is warranted.

 Keywords: Leishmaniasis; Epidemiological Trends; Saudi Arabia

 

References

  1. Alraey Y. “Distribution and epidemiological features of cutaneous leishmaniasis in Asir province, Saudi Arabia, from 2011 to 2020”. Journal of Infection and Public Health 15 (2022): 757-765.
  2. Pinheiro AC and de Souza MVN. “Current leishmaniasis drug discovery”. RSC Medicinal Chemistry 13 (2022): 1029-1043.
  3. Manual for case management of cutaneous leishmaniasis in the WHO Eastern Mediterranean Region (2014).
  4. Elmekki MA., et al. “Epidemiological trends of cutaneous leishmaniasis in Al-Madinah Al-Munawarah Province, Western Region of Saudi Arabia”. Journal of Global Infectious Diseases 9 (2017): 146-150.
  5. Maxfield L and Crane JS Leishmaniasis. “Treasure Island (FL)”. StatPearls Publishing (2022).
  6. Talas J., et al. “Cutaneous leishmaniasis in Germany-still a travel-related disease”. Hautarzt 73 (2022): 146-151.
  7. Desjeux P. “Leishmaniasis: public health aspects and control”. Clinics in Dermatology 14 (1996): 417-423.
  8. The Center for Disease Control and Prevention (CDC). “Parasites - Leishmaniasis Resources for Health Professionals” (2022).
  9. Burza S., et al. “Leishmaniasis”. Lancet 392 (2018): 951-970.
  10. Abuzaid AA., et al. “Cutaneous leishmaniasis in Saudi Arabia: a comprehensive overview”. Vector-Borne and Zoonotic Diseases 17 (2017): 673-684.
  11. Alvar J., et al. “Leishmaniasis worldwide and global estimates of its incidence”. PLoS 7 (2012): e35671.
  12. Sutherst RW. “Global change and human vulnerability to vector‑borne diseases”. Clinical Microbiology Reviews17 (2004): 136‑173.
  13. Ministry of Health. Health Statistical Yearbook. Saudi Arabia: Ministry of Health (2012).
  14. Amin TT., et al. “Cutaneous leishmaniasis in Al Hassa, Saudi Arabia: Epidemiological trends from 2000 to 2010”. Asian Pacific Journal of Tropical Medicine 6 (2013): 667‑672.
  15. Abuzaid AA., et al. “Visceral leishmaniasis in Saudi Arabia: From hundreds of cases to zero”. Acta Tropica 212 (2020): 105707.
  16. Li P., et al. Nested PCR detection of malaria directly using blood filter paper samples from epidemiological surveys”. Malaria Journal 175 (2014): 1-6.
  17. World Health Organization (WHO). Leishmaniasis (2022).
  18. Alanazi AD., et al. “Molecular characterization of Leishmania species from stray dogs and human patients in Saudi Arabia”. Parasitology Research 120 (2021): 4241-4246.
  19. Sirdar MK., et al. “Epidemiology and incidence of leishmaniasis in Jazan region, Saudi Arabia (2007-2015): an overview”. Journal of Entomology and Zoology Studies 6 (2018): 859-864.
  20. Bizri NA., et al. “The Association Between the Syrian Crisis and Cutaneous Leishmaniasis in Lebanon”. Acta Parasitologica 66 (2021): 1240-1245.
  21. Zakai HA. “Cutaneous leishmaniasis (CL) in Saudi Arabia: Current status”. Journal of Advanced Laboratory Research in Biology 5 (2014): 29‑34.
  22. Karami M., et al. “Assessing epidemiology of cutaneous leishmaniasis in Isfahan, Iran”. Journal of Vector Borne Diseases 50 (2013): 30‑37.
  23. Al‑Taqi M and Behbehani K. “Cutaneous leishmaniasis in Kuwait”. Annals of Tropical Medicine and Parasitology 74 (1980): 495‑501.
  24. Birjees MK. “Epidemiology of Cutaneous Leishmaniasis in Larkana District of Sindh Province with Particular Reference to Phlebotomine Sandflies: Public Health Division, National Institute of Health Islamabad, Pakistan (2001): 32.
  25. Morrone A., et al. “Epidemiological and geographical aspects of leishmaniasis in Tigray, Northern Ethiopia: A retrospective analysis of medical records, 2005‑2008”. Transactions of the Royal Society of Tropical Medicine and Hygiene 105 (2011): 273‑280.
  26. Adegboye OA. and Kotze D. “Disease mapping of leishmaniasis outbreak in Afghanistan: Spatial hierarchical Bayesian analysis”. Asian Pacific Journal of Tropical Disease 2 (2012): 253‑259.
  27. Al-Tawfiq JA and AbuKhamsin A. “Cutaneous leishmaniasis: a 46- year study of the epidemiology and clinical features in Saudi Arabia (1956-2002)”. International Journal of Infectious Diseases 8 (2004): 244-250.
  28. Bamba S., et al. “Trends in incidence of cutaneous leishmaniasis from 1999 to 2005 in Ouagadougou, Burkina”. Medecine Tropicale (Mars) 71 (2011): 312.
  29. Farahmand, et al. “An overview of a diagnostic and epidemiologic reappraisal of cutaneous leishmaniasis in Iran”. The Brazilian Journal of Infectious Diseases 15 (2011): 17-21.
  30. Abass E., et al. “Leishmaniasis in Saudi Arabia: Current situation and future perspectives”. Pakistan Journal of Medical Sciences 36 (2020): 836-842.
  31. Al-Rashed AS., et al. “Genotypic and phylogenic analyses of cutaneous leishmaniasis in Al Ahsa, Eastern Saudi Arabia during the coronavirus disease 2019 pandemic: First cases of Leishmania tropica with the predominance of Leishmania major”. Scientific Reports 12 (2022): 10753.

Citation

Citation: Raafat Abdel Moneim Hassanein., et al. “Leishmaniasis in the Kingdom of Saudi Arabia: Epidemiological Trends from 2019 to 2021: A Retrospective Study”.Acta Scientific Medical Sciences 7.9 (2023): 165-174.

Copyright

Copyright: © 2023 Raafat Abdel Moneim Hassanein., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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