Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 7 Issue 5

Features of Regeneration in the Area of Humerus Fracture on the Background of Osteoporosis

Konev VP, Moskovskij SN, Krivoshein AE, Sorokina VV, Shishkina YuO, Linnik MM, Saydasheva EM and Milto NS*

Omsk State Medical University, Omsk, Russia

*Corresponding Author: Milto NS, Resident, Omsk State Medical University, Omsk, Russia.

Received: February 14, 2023; Published: April 14, 2023

Abstract

The work is devoted to morphological studies in various types of humerus injury against the background of osteoporosis. Injury to the bone tissue triggers an additional cascade of processes, in which the central zone is dominated by the processes of bone tissue remodeling with the formation of granulation tissue, and the development of chondral callus. With an increase in the terms of mobilization in the fracture zone against the background of osteoporosis, histological signs of intermediary and endosteal callus are preserved. A lamellar bone with a compact organization, with a characteristic osteon structure, with primary strength characteristics in the fracture zone against the background of osteoporosis is no longer formed.In addition, against the background of osteoporosis with uneven calcification of bone and surrounding dense tissues, with inflammatory and degenerative-dystrophic processes, as well as due to prolonged mobilization of bones and joints, contractures of large joints are formed in the articular part of the bone and cartilage of the joint itself, accompanied by persistent restriction of movements, arthrosis and arthritis.

Keywords: Osteoporosis; Regeneration; Humerus; Fracture; Bone

References

  1. Zyabreva IA and Fomina LA. “The prevalence of osteoporosis in different age groups of Tver”. Youth, science, medicine: materials of the 60th interuniversity scientific conference of students (2014): 64-67.
  2. Konev VP., et al. “Osteoporosis as a background condition in mechanical trauma of flat and tubular bones”. Bulletin of Forensic Medicine 3 (2020): 12-16.
  3. Konev VP. “Osteoporosis as a manifestation of connective tissue dysplasia”. Therapy33 (2019): 74-80.
  4. Mikhanov VA., et al. “Reparative histogenesis of bone tissue in an open fracture of the diaphysis of the long tubular bone in rats using the Vinfar drug”. Modern problems of science and education 3 (2015) 162-170.
  5. Asilova SU., et al. “Morphological studies in osteoporosis of bones under experimental conditions”.
  6. Korzh NA and Dedukh NV. “Reparative bone regeneration: a modern view of the problem. Stages of regeneration”. Orthopedics, Traumatology and Prosthetics 1 (2016): 77-84.
  7. Rasulov HA. “Comparative assessment of morphological changes of the knee joint in patients with degenerative-dystrophic diseases when endoprosthetics are necessary”. Journal of Theoretical and Clinical Medicine 1 (2017): 91-95.
  8. Pobel EA. “Results of treatment of patients with diaphyseal fractures of long limb bones (retrospective analysis)”. Orthopedics, traumatology and prosthetics 4 (2012): 90-93.
  9. Nikitskaya OA., et al. “Early diagnosis of osteoporosis and the risk of osteoporotic fractures using the FRAX algorithm”. Ru. 80.2 (2013): 51-59.
  10. Solod EI., et al. “Features of treatment of various bones fractures in systemic osteoporosis”. Topical issues of traumatology. Progress. Prospects: Materials of the I scientific and practical conf (2013): 167-168.
  11. Castaño-Betancourt MC., et al. “Bone parameters across different types of hip osteoarthritis and their relationship to osteoporotic fracture risk”. Arthritis and Rheumatology 3 (2013): 693-700.
  12. Shevtsov VI., et al. “Age-related changes in the mineral density of skeletal bones”. The genius of orthopedics 1 (2004): 129-137.
  13. Burch J. “Systematic review of the use of bone turnover markers for monitoring the response to osteoporosis treatment: the secondary prevention of fractures, and primary prevention of fractures in high-risk groups”. Health and Technology 11 (2014): 1-180.
  14. Nguyen ND., et al. “Development of prognostic nomograms for individualizing 5-year and 10-year fracture risks”. Osteoporosis International10 (2008): 1431-1444.
  15. Fujiwara S., et al. “Development and application of a Japanese model of the WHO fracture risk assessment tool (FRAX™)”. International Osteoporosis Foundation and National Osteoporosis Foundation4 (2008): 429-435.

Citation

Citation: Milto NS., et al. “Features of Regeneration in the Area of Humerus Fracture on the Background of Osteoporosis”.Acta Scientific Medical Sciences 7.5 (2023): 113-119.

Copyright

Copyright: © 2023 Milto NS., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.403

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