Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Case Report Volume 7 Issue 3

A Rare Case of Typical Secretory Multiple Myeloma in a 21-Year-Old Man

Ahmad M Hassaneen1,2*

1Sulaiman AlRajhi University, Al Bukayriyah, Kingdom of Saudi Arabia
2Clinical Pathology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt

*Corresponding Author: Ahmad M Hassaneen, Sulaiman AlRajhi University, Al Bukayriyah, Kingdom of Saudi Arabia and Clinical Pathology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Received: January 31, 2023; Published: February 27, 2023


Introduction: Multiple myeloma is an important hematological malignancy in which plasma cells are increased in bone marrow. It is mainly a disease of elderly people ; the prevalence in patients younger than 40 years old is only 2%. However, in this case it has been diagnosed in a 21-year-old man which is considered a rare case report.

Method: A-21-year old Middle Eastern man presented to the author's institution with vague pain in the lumbar region. CT scan on vertebrae, urine testing for Bence Jones protein and serum protein electrophoresis (SPEP) have been done. Bone marrow aspiration has been done to detect plasma cells.

Results: CT scan showed multiple osteolytic lesions in the lumbar vertebrae. Urine was positive for Bence Jones protein and serum protein electrophoresis (SPEP) demonstrated M band.

Examination of bone marrow smears showed infiltration with 35% plasma cells, hence the diagnosis of multiple myeloma was established.

Conclusion: This report presents a rare case of typical secretory multiple myeloma in a 21-year -old man, which has been suspected clinically then confirmed by laboratory and radiological investigations. Suspecting this malignancy in young people is of clinical significance so that these cases will not be missed and early diagnosis and start of therapy can be achieved.

Keywords: Case Report; Multiple Myeloma; Plasma Cells; 21 Years Old


  1. Lonial S and Kaufman JL. “Non-secretory myeloma: a clinician’s guide”. Oncology (Williston Park)9 (2013): 924-928, 930.
  2. Dimopoulos M., et al. “Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3”. Blood 117 (2011): 4701-4705.
  3. Mondita Borgohain., et al. “Multiple Myeloma Presenting as Spinal Cord Compression: A Report of Five Cases”. International Journal of Contemporary Medical Research4 (2017): 837-839.
  4. Kazandjian D. “Multiple myeloma epidemiology and survival: a unique malignancy”. Seminar on Oncology 43 (2016): 676-681.
  5. Kyle RA., et al. “Review of 1027 patients with newly diagnosed multiple myeloma”. Mayo Clinic Proceedings 78 (2003): 21-33.
  6. Huynh Van Man and Phu Chi Dung. “A Case of Multiple Myeloma in a 17-Year-Old Girl Treated with Autologous Hematopoietic Stem Cell Transplantation (ASCT)”. American Journal of Case Reports 20 (2019): 1623-1629.
  7. Durie BG., et al. “International uniform response criteria for multiple myeloma”. Leukemia 20 (2006): 2220.
  8. Charlot-Lambrecht I., et al. “Myélome multiple EMC 2011-01-01”. 6.4 1-12.
  9. M Srija., et al. “Plasmablastic myeloma presenting as rapidly progressive renal failure in a young adult”. Indian Journal of Nephrology1 (2014): 41-44.
  10. Rajkumar SV., et al. “International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma”. Lancet Oncology12 (2014): e538-548.


Citation: Ahmad M Hassaneen. “A Rare Case of Typical Secretory Multiple Myeloma in a 21-Year-Old Man”.Acta Scientific Medical Sciences 7.3 (2023): 190-192.


Copyright: © 2022 Ahmad M Hassaneen. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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