Mariana-Alis Neagoe*

PhD Assistant Professor, "Titu Maiorescu" University - Faculty of Medicine, Bucharest and Memormed Medical Center – Bucharest, Romania

*Corresponding Author: Mariana-Alis Neagoe, PhD Assistant Professor, "Titu Maiorescu" University - Faculty of Medicine, Bucharest and Memormed Medical Center – Bucharest, Romania.

Received: January 30, 2023; Published: February 17, 2023

Abstract

Medical laboratory tests complement the medical check-up, playing an essential role in establishing a correct diagnosis. They confirm or refute certain suspicions of the disease. Depending on the specific clinical context of each patient, the physician will recommend medical laboratory tests, from routine tests to tests specific to certain conditions.

We present the case of a 73-year-old female patient, who presented to the medical office for fatigue arising from moderate exertion and breathing difficulties. Following the pulmonology check-up, it was decided to carry out a thoracic-pulmonary computer tomography (CT) which revealed fine bilateral infrahilar bronchiectasis and a voluminous round-oval process with axial dimensions of 39/26 mm located at the level of the prevascular space. It was decided to perform an anterior mediastinal puncture and the histopathological test revealed an aspect compatible with the diagnosis of type A thymoma. Considering the relationship between myasthenia gravis and tumours of the thymic gland, the diagnosis of myasthenia gravis was suspected.

Medical laboratory tests refuted the existence of anti-acetylcholine receptor antibodies. Anti-acetylcholine receptor antibodies are present in 80% of patients with generalized myasthenia gravis, which means that there are no current criteria for this diagnosis.

Medical laboratory tests can be the first line of detection of unusual events thus facilitating the establishment of an etiological diagnosis of suspicion or certainty.

Laboratory diagnosis plays an essential role in the correct clinical decision as well as in the optimal treatment for each patient.

 Keywords: Medical Laboratory Tests; Clinical Suspicion; Thymoma; Myasthenia Gravis; Thymectomy

References

1. Mungiu OC., et al. “Pain Therapy”. Etna Publishing House, Bucharest, (2018): 9.
2. Olăroiu M. “Treatment of palliative care at home”. Etna Publishing House, Bucharest (2015): 141.
3. Adams and Victor. “Principles and Practice of Clinical Neurology”. Callisto Medical Publishing House, Bucharest (2017): 1472.
4. Beers MH and Porter RS. “Merck Diagnostic and Treatment Manual”. ALL Publishing House, Bucharest, (2016): 1899.
5. Proca E. “Treatise on surgical pathology”. volume V, part III Medical Publishing House, Bucharest, (1991): 274-276.
6. Martin AS and Allan HR. “Samuels manual of neurologic therapeutics”. Wolters Kluwer Publishing House, Philadelphia, (2017): 238.
7. Kister I and Biller J. “Top 100 Diagnoses in Neurology”. Wolter Kluwer Publishing House, Philadelphia, (2021): 57.
8. Joseph SK and Eli MM. “Neurology secrets”. Elsevier Publishing House, Philadelphia, (2017): 67-68.

Citation

Citation: Mariana-Alis Neagoe. “Clinical Suspicion Refuted by Laboratory Tests”.Acta Scientific Medical Sciences 7.3 (2023): 145-147.

Copyright

Copyright: © 2022 Mariana-Alis Neagoe. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.