Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Case Report Volume 7 Issue 1

Adult - Onset Still’s Disease - Case Report

Tenzin Gyaltsen*, Ajay Gowda, Sarath Chandran Kr, Satyajit Hajong, Nitajan Nongtdu and Gido Pertin

PGTs in Department of General Medicine, Regional Institute of Medical Sciences, Imphal, India

*Corresponding Author: Tenzin Gyaltsen, PGTs in Department of General Medicine, Regional Institute of Medical Sciences, Imphal, India.

Received: November 29, 2022; Published: December 28, 2022

Abstract

Background: Adult onset still’s disease (AOSD) is a rare multisystemic inflammatory disorder with an unknown etiology. Many theories have been put forward to understand the pathogenesis of the disease. The sign, symptoms and severity of the disease vary among different individuals. The affected person generally present with arthritis, spiking fever with pink colored rash, muscle, joint pain and with other systemic presentations. Diagnosis is generally made after thorough clinical examination which requires exclusion of other conditions which mimics same presentation such as infection, malignancy and autoinflammatory condition before labeling a patient to be affected with AOSD.

With the above background, we report a case of 42 yrs. female who presented with joint pain, fever, sore throat and pink colour  rash predominantly on trunk and lower limbs which generally decreased whenever fever subsided (evanescent) since one year.  On clinical examination patient had cervical and right inguinal lymphadenopathy with splenomegaly. Laboratory test showed anemia, neutrophilic leukocytosis, raised liver enzymes and hyperferritinemia. After excluding the all the potential causes for the patient's condition, she was diagnosed to have AOSD based on Yamaguchi criteria. On treating the patient with corticosteroids and NSAIDs patient improved symptomatically.

Keywords: AOSD: Adult - Onset Still’s Disease

References

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  2. Bywaters EG. “Still's disease in the adult”. Annals of the Rheumatic Diseases 2 (1971): 121-133.
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  4. Magadur-Joly G., et al. “Epidemiology of adult Still's disease: estimate of the incidence by a retrospective study in west France”. Annals of the Rheumatic Diseases 7 (1995): 587-590.
  5. Yamaguchi M., et al. “Preliminary criteria for classification of adult Still's disease”. Journal of Rheumatology 3 (1992): 424-430.
  6. Efthimiou P and Georgy S. “Pathogenesis and management of adult-onset Still's disease”. Seminars in Arthritis and Rheumatism 3 (2006): 144-152.
  7. Kelly J., et al. “Sore throat and hyperferritinaemia”. Journal of the Royal Society of Medicine 8 (2001): 400-401.

Citation

Citation: Tenzin Gyaltsen., et al. “Adult - Onset Still’s Disease - Case Report”.Acta Scientific Medical Sciences 7.1 (2023): 80-82.

Copyright

Copyright: © 2022 Tenzin Gyaltsen., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.403

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