Zeenat Ara¹, Devarshi Rastogi¹, Aftab Alam Khan² and Shah Waliullah¹*

¹Department of Orthopaedic Surgery, King George’s Medical University, Shahmina Road, Chowk, Lucknow, Uttar Pradesh, India
²First Moscow State Medical University, Moscow, Russia

*Corresponding Author: Shah Waliullah, Department of Orthopaedic Surgery, King George’s Medical University, Shahmina Road, Chowk, Lucknow, Uttar Pradesh, India.

Received: August 01, 2022; Published: August 29, 2022

Abstract

Taurine (Tau), a sulphur containing amino acid, chemically known as 2 aminoethane sulphonic acid, it’s a non-proteinogenic β-amino acid, often referred to as semi essential amino acid as new born mammals have very limited ability to synthesize taurine and they have to depend on dietary sources, it is not incorporated into proteins as no aminoacyl tRNA synthetase has yet been identified and is not oxidized in mammalian cells, it attains an important place because of the antioxidant defence network. It has multiple function in the CNS, it serves as an osmoregulator, antioxidant, inhibitory neuromodulator, and regulator of intracellular Ca2flux.First time when it was discovered from ox bile by the German professors Friedrich Tiedemann and Leopold Gmelin they named it Gallen‑Asparagin, later it was known as taurus, in latin Bos taurus means Ox, but it attains its current name (Taurine) in 1838 by von H. Demarcay. Because of presence of sulphonic acid instead of carboxylic acid it is not metabolized and not involved in gluconeogenesis and thus not envolve in direct energy sources. Taurine is produced by liver and kidney including retina, brain, heart and placenta. Taurine plays extensive role against different disorders of the body and in deadly diseases like cancer, liver cirrhosis etc. Human body contains about 0.1% of body weight as taurine. It has a number of physiological and pharmacological actions. In case of spinal cord injury elevated level of taurine has been seen, In methyl prednisolone (MP), treatment in case of SCI, elevation in level of taurine is observed, this elevated level seems to be involved in protection and regeneration of tissues following injury. In this review we try to cover every possible role of taurine which may provide enough information for future research.

Keywords: SCI; Tau; ZEN; Hcy; PSA; AMK; SCI; ASIA Scale; Osteoporosis

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Citation

Citation: Shah Waliullah., et al. “Role of Taurine and its Analogs Against Various Disorders and its Beneficial Effects: A Review Article”.Acta Scientific Medical Sciences 6.9 (2022): 95-115.

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Copyright: © 2022 Shah Waliullah., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.