Acta Scientific MEDICAL SCIENCES (ISSN: 2582-0931)

Research Article Volume 6 Issue 7

Neurological Manifestations and Complications of COVID-19 in Jouf Region

Waleed Seif El-Din Mohamed1*, Hisham Abid Aldabbagh2, Mohammed Ghazi Thani Alruwaili2, Khaled Zeki Fouda3, Mohamed Fawzy Ibrahim4, Iman Adel Abdel-Almoniem5 Refah Muflih Alazmi2 and Zarifa Matar Salem Al Atawi2

1Clinical Laboratory Department, College of Applied Medical Sciences, Jouf University, KSA
2Qurayyat General Hospital, Directorate of Health Affairs in Qurayyat, Ministry of Health, KSA
3Department of Basic Science for Physical Therapy, Faculty of Physical Therapy, Cairo University, Egypt
4Paediatric Oncology Department, Egypt
5Surgical Pathology Department, National Cancer Institute, Cairo University, Egypt

*Corresponding Author:Waleed Seif El-Din Mohamed, Clinical Laboratory Department, College of Applied Medical Sciences, Jouf University, KSA.

Received: April 14, 2022; Published: June 15, 2022


Background: The coronavirus pandemic has overwhelmed the health scene in almost all world countries including Middle East region. Neurological manifestations and complications are frequently reported among Covid-19 patients.

Aim of work: To focus on Neurological Manifestations and Complications of COVID-19, aiming to add more clearance of these Manifestations and Complications and their outcomes in COVID-19 patients.Patients and Methods: The present retrospective study was conducted on 127 COVID 19 patients who were admitted at Qurayyat general hospital from 01-01-2020 to 31-12-2020, in addition to other 127 patients without neurological manifestations (as a control group) recruited from other departments.

Results: Comparison between both groups shows that patients with neurological manifestations are significantly older (61.52 ± 51.29 versus 43.2 ± 19.8 years, p = 0.001). Also, they had significantly higher frequency of Diabetes mellitus (DM) comorbidities (41/127 (32.3%) versus 20/127 (15.7%), p = 0.02), and higher frequency of Hypertension (HTN) comorbidities (54/127 (42.5%) versus 18/127 (14.1%), p = 0.001). In addition, they had significantly higher frequency of chronic obstructive pulmonary disease (COPD) comorbidities (17/127 (13.4%) versus 2/127 (1.6%), p = 0.04). For Chronic kidney disease (CKD), there was a statistically significant difference (p = 0.023) between patients with/or without neurological manifestations. Regarding predictors of mortality in the studied patients, Diabetes Mellitus [OR (95% CI): 1.31 (1.11-1.56), p = 0.01], and presence of neurological manifestations [OR (95% CI): 0.29 (0.14-0.9), p = 0.03] demonstrated as independent risk factors with COVID-19 mortality.

Conclusion: The current study has demonstrated that neurological manifestations are common in Covid-19 patients. Also, diabetes mellitus and presence of neurological manifestations may be considered as two independent risk factors with COVID-19 mortality.

Keywords: Covid-19; Neurological Manifestations and Complications; Covid-19 Mortality


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Citation: Waleed Seif El-Din Mohamed., et al. “Neurological Manifestations and Complications of COVID-19 in Jouf Region". Acta Scientific Medical Sciences 6.7 (2022): 184-188.


Copyright: © 2022 Waleed Seif El-Din Mohamed., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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