Waleed Seif El-Din Mohamed¹*, Hisham Abid Aldabbagh², Mohammed Ghazi Thani Alruwaili², Khaled Zeki Fouda³, Mohamed Fawzy Ibrahim⁴, Iman Adel Abdel-Almoniem⁵ Refah Muflih Alazmi² and Zarifa Matar Salem Al Atawi²

¹Clinical Laboratory Department, College of Applied Medical Sciences, Jouf University, KSA
²Qurayyat General Hospital, Directorate of Health Affairs in Qurayyat, Ministry of Health, KSA
³Department of Basic Science for Physical Therapy, Faculty of Physical Therapy, Cairo University, Egypt
⁴Paediatric Oncology Department, Egypt
⁵Surgical Pathology Department, National Cancer Institute, Cairo University, Egypt

*Corresponding Author:Waleed Seif El-Din Mohamed, Clinical Laboratory Department, College of Applied Medical Sciences, Jouf University, KSA.

Received: April 14, 2022; Published: June 15, 2022

Abstract

Background: The coronavirus pandemic has overwhelmed the health scene in almost all world countries including Middle East region. Neurological manifestations and complications are frequently reported among Covid-19 patients.

Aim of work: To focus on Neurological Manifestations and Complications of COVID-19, aiming to add more clearance of these Manifestations and Complications and their outcomes in COVID-19 patients.Patients and Methods: The present retrospective study was conducted on 127 COVID 19 patients who were admitted at Qurayyat general hospital from 01-01-2020 to 31-12-2020, in addition to other 127 patients without neurological manifestations (as a control group) recruited from other departments.

Results: Comparison between both groups shows that patients with neurological manifestations are significantly older (61.52 ± 51.29 versus 43.2 ± 19.8 years, p = 0.001). Also, they had significantly higher frequency of Diabetes mellitus (DM) comorbidities (41/127 (32.3%) versus 20/127 (15.7%), p = 0.02), and higher frequency of Hypertension (HTN) comorbidities (54/127 (42.5%) versus 18/127 (14.1%), p = 0.001). In addition, they had significantly higher frequency of chronic obstructive pulmonary disease (COPD) comorbidities (17/127 (13.4%) versus 2/127 (1.6%), p = 0.04). For Chronic kidney disease (CKD), there was a statistically significant difference (p = 0.023) between patients with/or without neurological manifestations. Regarding predictors of mortality in the studied patients, Diabetes Mellitus [OR (95% CI): 1.31 (1.11-1.56), p = 0.01], and presence of neurological manifestations [OR (95% CI): 0.29 (0.14-0.9), p = 0.03] demonstrated as independent risk factors with COVID-19 mortality.

Conclusion: The current study has demonstrated that neurological manifestations are common in Covid-19 patients. Also, diabetes mellitus and presence of neurological manifestations may be considered as two independent risk factors with COVID-19 mortality.

Keywords: Covid-19; Neurological Manifestations and Complications; Covid-19 Mortality

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Citation

Citation: Waleed Seif El-Din Mohamed., et al. “Neurological Manifestations and Complications of COVID-19 in Jouf Region". Acta Scientific Medical Sciences 6.7 (2022): 184-188.

Copyright

Copyright: © 2022 Waleed Seif El-Din Mohamed., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.