Prevalence and Risk Factors of Thrombocytopenia in a Medical Intensive Care Unit in Egypt
Ahmad M Hassaneen1,2*
1Sulaiman AlRajhi University, Al Bukayriyah, Kingdom of Saudi Arabia
2Clinical Pathology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt
*Corresponding Author: Ahmad M Hassaneen, Sulaiman AlRajhi University, Al Bukayriyah, Kingdom of Saudi Arabia.
March 21, 2022; Published: May 09, 2022
Background: Thrombocytopenia is a very common complication in the intensive care unit and is considered an important prognostic factor. The important possible mechanisms for thrombocytopenia include disseminated intravascular coagulation, sepsis, massive hemorrhage, the use of heparin and antibiotics.
Aim of Study: This study aimed to determine the prevalence and risk factors of thrombocytopenia in the medical intensive care unit in Zagazig University hospitals in Egypt.
Patients and Methods: This observational, cross-sectional study was conducted on 140 patients (78 males and 62 females) in the medical intensive care unit. Present and past history was taken, and platelets count was estimated every day until discharge to detect thrombocytopenia.
Results: Thrombocytopenia was detected in 94 patients, with a prevalence of 67% (53 males and 41 females). Regarding age, 56% of cases were above the age of 60 years. The main risk factors for development of thrombocytopenia in this study were sepsis, antibiotics, heparin and mechanical ventilation as there was a significant difference between patients with and those without thrombocytopenia regarding these factors. On the other hand, there was no significant difference regarding duration of ICU stay, invasive catheters or coronary artery disease.
Conclusion: Thrombocytopenia is a common complication in ICU patients. The main risk factors are sepsis, antibiotics, heparin and mechanical ventilation.
Keywords: Thrombocytopenia; Intensive Care Unit; Prevalence; Risk Factors
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