Green Chemistry: Phyto-antibiotics, A Green Antibiotics, Isolated from Medicinal Plant of West Bengal Targeting Multi-drug Resistant Bacteria
Sanatan Das, Sankalita Datta, Madhumita Dey, Kousik Poria and Asit Kumar Chakraborty*
Department of Biotechnology and Biochemistry, Genetic Engineering Laboratory, Oriental Institute of Science and Technology, West Bengal, India
*Corresponding Author: Asit Kumar Chakraborty, Department of Biotechnology and Biochemistry, Genetic Engineering Laboratory, Oriental Institute of Science and Technology, West Bengal, India, author:email@example.com and mobile no. +917679154141, pincode of Midnapore-721102.
February 21, 2022; Published: April 20, 2022
Today green chemistry approaches have been introduced to reduced toxicity and environmental pollution. Interestingly, use of huge synthetic antibiotics caused generation of drug resistant bacteria with increased generation and amplification of mdr genes (bla, amp, tet, str, aph, aac, cat) and transposons (IS5, IS30, IS110 etc) in large plasmids. We coined the green antibiotics word to introduce phyto-chemicals that inhibited bacteria with specificity similar to synthetic drugs. Ideally plants secret anti-metabolites to retard the growth of microorganisms and thus a good source for new drug development. We explored the isolation and characterization of six organic plant extracts from medicinal plants of West Bengal. In truth, Taxol, Artiminisin, Etoposide and Camptothecin are well documented phyto-drugs used as anti-cancer and anti-parasitic drugs.>
Keywords: Green Antibiotics; Heterogeneous Phyto-antibiotics; MDR-TB; MDR-Typhoid; Corona Virus Infection; Indian Medicinal Plants
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