Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 6 Issue 3

Headache and Covid-19: Experience from the Covid-Centre at the University Clinic of Neurology in Skopje

Popovska H1*, Petrov I2, Kiteva-Trencevska G2, Popovski N3 and Filipovic D4

1University Clinic of Neurology, Skopje, Republic of Macedonia
2Professor, University Clinic of Neurology, Skopje, Republic of Macedonia
3University Clinic of Orthopedic Surgery, Skopje, Republic of Macedonia
4University Clinic of Dermatology and Venereology, Skopje, Republic of Macedonia

*Corresponding Author: Popovska H, University Clinic of Neurology, Skopje, Republic of Macedonia.

Received: May 16, 2021; Published: February 15, 2022

Abstract

Introduction: Corona virus infectious disease 2019, (Corona virus disease-19, Covid-19), commonly is manifested with severe respiratory syndrome and interstitial pneumonia. Beside these respiratory symptoms, the clinical spectrum of the disease consists of neurological symptoms. A headache is one of them.

Aim: The aim of this study is to determine the cumulative prevalence of a headache in patients with Covid-19, that were hospitalized at the Clinic of neurology in Skopje, from November 2020 to the end of March 2021. This study also aimed to determine the cumulative prevalence of patients with positive outcome and successful rehabilitation and, on the other side, the prevalence of the patients with poor outcome.

Methods and Materials: The data was extracted from HIS system (electronic data base for outpatient clinic and hospitalized patients in our Clinic). In the study were included 437 patients, hospitalized in the Covid –centre. We have calculated the cumulative prevalence of headache in these patients. Additionally, we have determined the prevalence of headache in patients with good and with poor outcome of the disease.

Results: Headache was found in 44 patients out of 437, with confirmed Covid-19 infection. The estimated cumulative prevalence is 10.06%. The patients with headache had more favorable outcome of the COVID-19 infection (37 patients out of 270 with favorable outcome has complained of a headache in the early stage of the disease, and only 4 patients out of 120 with fatal outcome, had a headache (P = .002058, (P < .05)). Three patients, who have complained of a headache, out of 47, were transferred to another medical institution.

Conclusion: Headache is a common symptom among patients with infectious diseases, whether it is a part of the general infectious syndrome or it is a sign of a direct cerebral affection. The headache could be a predictive symptom for more favorable outcome of this infectious disease.

Keywords: Headache; Covid-19; Prevalence

References

  1. Endang Mutiawati., et al. “Global prevalence and pathogenesis of headache in COVID-19: A systematic review and meta-analysis”. F1000Research 9 (2021): 1316.
  2. Özge Uygun., et al. “Headache characteristics in COVID-19 pandemic-a survey study”. The Journal of Headache and Pain 21 (2020): 121.
  3. Hayrunnisa Bolay., et al. “COVID-19 is a Real Headache!” Headache (2020): 1-7.
  4. Mehran Ghaffari., et al. “Neurological features and outcome in COVID 19: dementia can predict severe disease”. Journal of NeuroVirology 27 (2021): 86-93.
  5. Vaibhav Seth., et al. “Headache Due to COVID-19: A Disabling Combination”. Headache 60 (2020): 2618-2621.
  6. I Putu Eka Widyadharma., et al. “Pain as clinical manifestations of COVID-19 infection and its management in the pandemic era: a literature review”. The Egyptian Journal of Neurology, Psychiatry and Neurosurgery 56 (2020): 121.
  7. Robert E Shapiro., et al. “The impact of headache disorders on COVID-19 survival: a world population-based analysis” (2021).
  8. Javier Trigo., et al. “Factors associated with the presence of headache in hospitalized COVID-19 patients and impact on prognosis: a retrospective cohort study”. The Journal of Headache and Pain 21 (2020): 94.
  9. Asiful I., et al. “Prevalence of Headache in Patients With Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-Analysis of 14,275 Patients”. Frontiers in Neurology (2020).

Citation

Citation: Popovska H., et al. “Headache and Covid-19: Experience from the Covid-Centre at the University Clinic of Neurology in Skopje”.Acta Scientific Medical Sciences 6.3 (2022): 72-75.

Copyright

Copyright: © 2022 Popovska H., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.403

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