Elizabeth Guelmo-Daisley*, Shiva Sarwan, Ariadne Saunders and Osei Fraser
Department of Surgery, Port-Of-Spain General Hospital, Trinidad
*Corresponding Author: Elizabeth Guelmo-Daisley, Department of Surgery, Port-Of-Spain General Hospital, Trinidad.
Received: December 01, 2021; Published: January 17, 2022
Background: Autoimmune pancreatitis (AIP) is commonly found in Asia and Japan but its incidence in most of the western world is yet to be determined. There are two histologically distinct forms of the disease: type 1 and type 2 AIP. AIP may appear clinically and radiologically similar to pancreatic adenocarcinoma, but with fundamentally different treatment strategies.
Case Presentation: A non-alcoholic 42-year-old female with no medical issues presented with painless and progressive clinical and biochemical obstructive jaundice. Initial focused hepatobiliary ultrasound excluded cholelithiasis, and CECT and MRI abdomen with contrast/MRCP imaging of the biliary tree was highly suggestive of a pancreatic head neoplasm. Her Ca 19.9 levels were elevated and her IgG4 serology was normal. A pancreaticoduodenectomy was done. Histological examination of the specimen revealed nil evidence of pancreatic adenocarcinoma, but a robust lymphoplasmacytic inflammatory infiltrate with storiform fibrosis in keeping with autoimmune pancreatitis.
Discussion: Despite the existence of and adherence to robust AIP international guidelines, pancreatic pseudotumours represent a distinct clinical entity that is difficult to distinguish from pancreatic adenocarcinoma based on clinical, radiological and serological investigations. Thus, the incidence of patients having unnecessary surgery for AIP due to misdiagnosis remains around 9.9%, with the inherent associated morbidity .
Keywords: Autoimmune Pancreatitis; Biliary Tree; Pancreatic Adenocarcinoma
Citation: Elizabeth Guelmo-Daisley., et al. “Pancreatic Pseudotumour in Seronegative Autoimmune Pancreatitis: A Rare case in the Caribbean”.Acta Scientific Medical Sciences 6.2 (2022): 100-104.
Copyright: © 2022 Elizabeth Guelmo-Daisley., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.