Bacteriological Quality of Commonly Dispensed Non-prescription Drugs (Tablets) Sold in Patent Medicine Stores
Nwachukwu O Ndubuisi1*, Ezeagwula Divine1, Onyeagba A Reginald1, Unegbu N Valentine2 and Owanta I Julie1
1Department of Microbiology, Abia State University, Abia State, Nigeria
2Department of Biology, Spiritan University, Abia State, Nigeria
*Corresponding Author: Nwachukwu O Ndubuisi, Department of Microbiology, Abia State University, Abia State, Nigeria.
December 16, 2021; Published: January 13, 2022
Commonly consumed nonprescription oral dosage forms (tables) dispensed from Patent Medicine Stores are subject to unrestricted handling and potential contamination by microorganisms. We determined the bacteriological quality of tablets sold from patent medicine stores in Umuahia, Nigeria. A total of 113 items of 24 registered tablet brands were purchased. They were investigated for total bacterial count and presence of specified microorganisms using standard microbiological methods. Out of 113 items, 84(74.3%) tablets were free of microbial contamination while 14(12.4%) had bacterial counts <102 cfu/ml. Only 2(1.8%) tablets exceeded the specified bacterial limit of >2x103 cfu/ml. None of the blister-packed tablets had bacterial growth on them. All the tablets dispensed (“counted”) from large containers were contaminated by aerobic bacteria. The commonly encountered bacterial contaminants were Staphylococcus aureus and Bacillus species. Folic acid and Magnesium trisilicate were the most contaminated tablets. The tablets in blister packs were of excellent bacteriological quality.
Keywords: Bacteriological Quality; Patent Medicine Stores; Commonly Dispensed; Non Prescription Tablets
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