Dheba Mohammed Abobaker¹, Salem Mohamed Edrah²*, Sarah Jarood³, Hanan Alnade⁴, Wesam A Kollab⁴

¹Chemistry Department, Science College, Alzawia University, Alzawia Libya
²Chemistry Department, Science College, ElMergib University, Al-Khums Libya
³Chemistry Department, Faculty of Postgraduate Study, ElMergib University, Al-Khums Libya
⁴Chemistry Department, Faculty of Science, Alasmarya Islamic University, Zliten Libya

*Corresponding Author: Salem Mohamed Edrah, Chemistry Department, Science College, ElMergib University, Al-Khums Libya.

Received: October 29, 2021; Published: December 23, 2021;

Abstract

Plants are a source of a great abundance of drugs including several groups such as antimicrobials, anticancer, antispasmodics, etc. A large number of the plants are own antibiotic characteristics in conventional usage and are also utilised widely by the tribal people extensive.

Objectives: Thyme is one of the vital plants around the world because it contains various essential secondary metabolites which are considered as bioactive ingredients for the remedy of several diseases. The present study aimed to a qualitative and quantitative phytochemical screening of RE, preparation of a boiled mixture of thyme leaves and goat's milk TMGT as a traditional drug, and examination of the biological activity of each of RE and TMGT against some sorts of pathogenic bacteria.

Methodology: Preparation of Thyme-Milk Goat's Treatment (TMGT): where fresh wild thyme leaves were added to fresh goat's milk, and mixed very well, followed by added virgin olives oil with well mixing, and boiled a while, a thick, yellowish-oily liquid {Thyme-Milk Goat's Treatment (TMGT)} was obtained.

Preparation of Thyme Aqueous Raw Extract (RE): Where a coarsely fine powdered of thyme leaves was extracted with appropriated solvent by using soxhlet extractor apparatus.

Results: Percentage Yields: The percentage yields of RE were 89%, while the pH for RE and TGMT were 6.7 and 7.3, individually, and the acid value of raw goat’s milk was 6.7g.

Preliminary Phytochemical Screening: The preliminary phytochemical screening of thyme aqueous crude extract revealed the presence of plentiful amounts of bioactive ingredients, which are tannins, phenols, Fats and Fixed oils, Amino acids alkaloid, flavonoids and steroids and triterpenoids.

Quantitative Phytochemical Investigation: The percentage yields obtained from the leaves regarding quantitative phytochemical investigation were 81, 72 and 90 % for Flavonoids Alkaloids and Saponins, separately.

Antibacterial: The thyme aqueous raw extract (RE) was tested against each of the bacterial; Escherichia coli, Staphylococcus aureus, Lactobacillus, Streptococcus pneumonia and Staphylococcus aureus, were revealed 19, 20, 21, 19 and 23 mm, correspondingly. However, the TMGT showed 23, 22, 25, 24 and 25 mm consistently.

Keywords: Thymus vulgaris L.; Thyme-Milk Goat's Treatment; Phytochemical Screening; Pathogenic Bacterial

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Citation

Citation: Salem Mohamed Edrah., et al. “Phytochemical Examination and Antibacterial Activities of Thyme Leaves and their Use with Goat's Milk as a Traditional Remedy". Acta Scientific Medical Sciences 6.1 (2021): 259-269.

Copyright

Copyright: © 2021 Salem Mohamed Edrah., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.