Luljeta Abdullahu MD¹*, Violeta Grajqevci MD PhD²*, Naser Gjonbalaj MD PhD³, Fitore Murati-Abdullahu⁴, Vjollca Dedushaj-Fazliu Mr Sci⁵ and Mimoza Berbatovci Ukimeraj MD PhD⁶

¹Department of Nuclear Medicine, University Clinical Center of Kosova, Republic of Kosovo

*Corresponding Author: Luljeta Abdullahu, Department of Nuclear Medicine, University Clinical Center of Kosova, Republic of Kosovo. E-mail: luljeta.ab@gmail.com and Violeta Grajçevci MD PhD, Clinic of Pediatric-Hemato-oncology Department, University Clinical Center of Kosova, Republic of Kosovo. E-mail: violetagrajqevci@hotmail.com

Received: June 25, 2020; Published: November 17, 2021

Abstract

The Goal: Quantification and classification of Hydronephrosis in children with Nuclear Medicine diagnostic method.

Methods: Retrospective study that has involved 49 pediatric patients in the time period from January to October 2015 at the age group from 2003 to 2015 (with an average age of 4.0 years). Dynamic study of the kidney is made with the protocol predefined study duration of 20 min for time of 99m Tc-DTPA administration-that. The images were taken with two detectors gamma camera with a low energy collimators and high resolution power in the rear projection.

Results: Of 49 patients to examine the dynamic kidney scintigraphy, 34 (69%) showed signs of morphological (anatomical) and functional hydronephrosis in varying degrees of development caused by different causes. The study included 19 (40%) cases of female with an average age of 4.68 years, and 30 cases were male (60%) with an average age of 3.86 years. Hydronephrosis of 34 cases with 14 females (41.17%) and 20 males (58.82%).

Conclusion: The method provides accurate high-quality diagnostic determination of the case of hydronephrosis, together with the test with "forced" diuresis predicts the nature of significant impairments in function and helps in the early detection of deterioration of functional mass.

Keywords: Hydronephrosa; Dynamic Renal Scan; 99m Tc-DTPA; Test with "Forced" Furosemide Diuresis; Ecam-gamma Camera

References

1. Cortes D., et al. “[Prenatal diagnosed hydronephrosis and other urological anomalies]”. Ugeskr Laeger 168 (2006): 2544-2550.
2. Homsy YL., et al. “Transitional hydronephrosis of the newborn and infant”. The Journal of Urology 144 (1990): 579-583.
3. Int’l Consens. Comm.Semin NM ‘99:146-159 International Consensus Committee Recommendations for Basic Renogram Taylor, Semin NM 9 146-159.
4. Piepsz A and Ham HR. “Pediatric applications of renal nuclear medicine”. Seminars in Nuclear Medicine1 (2006): 16-35.
5. Sampson C. “Textbook of Radiopharmacy”. 3^rd Amsterdam: Gordon and Breach (1999).
6. Kao PF., et al. “The 99mTc DMSA renal scan and 99mTc-DTPA diuretic renogram in children and adolescents with incidental diagnosis of horseshoe kidney”. Nuclear Medicine 24 (2003): 525-530.
7. Steiner D., et al. “The value of renal scintigraphy during controlled diuresis in children with hydronephrosis”. European Journal of Nuclear Medicine and Molecular Imaging 26 (1999): 18-21.
8. British Society of Nuclear Medicine. Dynamic Renal Radionuclide Studies (2003).
9. O'Reilly P., et al. “Consensus on diuresis renography for investigating the dilated upper urinary tract. Radionuclides in Nephrourology Group. Consensus committee on Diuresis Renography”. The Journal of Nuclear Medicine 37 (1996): 1872-1876.
10. Rao S. “Obstructive Uropathy, Acute (2009).
11. Koff SA. “Requirements for accurately diagnosing chronic partial upper urinary tract obstruction in children with hydronephrosis”. Pediatric Radiology1 (2008): 41-48.
12. Br JUrol 1987:10-14 Upsdell, Br JUrol (1992): 126-132.
13. Dudley JA., et al. “Clinical relevance and implications of antenatal hydronephrosis”. Archives of Disease in Childhood: Fetal and Neonatal Edition 76 (1997): F31-34.
14. Arena S., et al. “A long-term follow-up in conservative management of unilateral ureteropelvic junction obstruction with poor drainage and good renal function”. European Journal of Pediatrics 177 (2018): 1761-1765.
15. Yiee J and Wilcox D. “Management of fetal hydronephrosis”. Pediatric Nephrology 23 (2008): 347-353.
16. Karnak I., et al. “Prenatally detected ureteropelvic junction obstruction: clinical features and associated urologic abnormalities”. Pediatric Surgery International 24 (2008): 395-402.
17. Gordon I., et al. “Pelvis retentive junction obstruction: The value of post micturition view in Tc99m DTPA diuretic demography”. Brazilian Journal of Urology 61 (1988): 409-412.
18. Toiviainen-Salo S., et al. “Fetal hydronephrosis: is there a hope for consensus?” Pediatric Radiology4 (2004): 519-529.
19. Gordon I. “Pathophysiology of renal function and its effect on isotope studies in the workup of hydronephrosis”. World Journal of Urology 22 (2004): 411-414.
20. Blaufox MD., et al. “Report of the Radionuclides in Nephrourology Committee on renal clearance”. The Journal of Nuclear Medicine 37 (1996): 1883-1890.

Citation

Citation: Luljeta Abdullahu., et al. “Hydronephrosis In Children and Kidney Dynamic Scintigraphy". Acta Scientific Medical Sciences 5.12 (2021): 74-80.

Copyright

Copyright: © 2021 Luljeta Abdullahu., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.