Professor of Chest Diseases, Tishreen University, Lattakia and Syrian Private University-Damascus, Syria
*Corresponding Author: Yousser Mohammad, Professor of Chest Diseases, Tishreen University, Lattakia and Syrian Private University-Damascus, Syria.
Received: August 12, 2021; Published: November 11, 2021
Introduction: The diagnosis of Community-Acquired Pneumonia is clinical and radiological. Its treatment by antibiotics is empirical. Performing biological tests to identify the causal microbe is recommended only in the case of severity and hospitalization (CRB65,PSI), and also if there is no response to empirical antibiotic therapy. However, in developing countries, microbes not included in international guidelines - such as tuberculosis and other unusual microbes - could be causal.
Methods: We surveyed 110 cases of Community-Acquired Pneumonia consulting the outpatient clinic of Tishreen University Hospital, Lattakia.
Results: 98/110 cases responded to treatment by macrolides/beta lactams. But the remaining12 did not. Among these 12 cases, we isolated Tuberculosis bacilli in 10 (5 in sputum, and 5 in BAL), who were successfully treated with anti-tuberculosis protocols.
For one case, the serodiagnosis Vidal for Salmonella typhi was positive 1/320, and was treated with success.
The last case of the 12 was the most surprising. There was no response to empirical antibiotics, non tuberculosis bacilli isolated. All cultures and serodiagnosis were negative, but, in the antecedents, we found splenectomy for ameombiasis. We performed a lung biopsy and were surprised to see Entamoeba histolytica in the lesion. We treated this case with metronidazole and were successful.
Conclusion: International guidelines for CAP management should be provided to developing countries for special causal microbes: above all under the guise of pneumonia tuberculosis can occur, but also other endemic microbes like Salmonella typhi and ameobiasis.
Keywords: Community Acquired Pneumonia; Developing Countries; Ameobiasis; Salmonella
Citation: Yousser Mohammad. “Unusual Microbes for Community-Acquired Pneumonia". Acta Scientific Medical Sciences 5.12 (2021): 26-28.
Copyright: © 2021 Yousser Mohammad. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.