Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 5 Issue 6

Sickle Cell Osteonecrosis, Report of 31 Cases in Congo Brazzaville

Affleck Romaric Ledier Angalla1,2*, Norbert Lamini1,2, Akoli Ekoya2, Chabel Nkouala Kidédé2, Francina Omboumahou Bakale2, AP Salémo2 and Honoré Ntsiba1,2

1Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Congo
2Department of Rheumatology, Brazzaville University Hospital Center, Brazzaville, Congo

*Corresponding Author: Affleck Romaric Ledier Angalla, Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Congo.

Received: January 17, 2021; Published: May 14, 2021


Goal: Improve the management of osteonecrosis in sickle cell patients.

Materials and Methods: Retrospective study, conducted from January 1, 2001 to June 30, 2010, i.e. 9 years and 6 months in the departments of Rheumatology, Clinical Hematology, Orthopedic Traumatology, Childhood Surgery and Pediatrics Grand Children of the University Hospital of Brazzaville-Congo. The diagnosis of sickle cell osteonecrosis was made based on anamnestic, clinical and paraclinical arguments (radiological classification by Arlet and Ficat).

Results: We included 31 cases of sickle cell osteonecrosis (0.6%), including 18 female (58.1%) and 13 male (41.9%), with a sex ratio of 0.72 (M/F). The mean age was 25.6 years (range 10 and 44). The hip was the seat of the most common osteonecrosis: left unilateral in 15 cases (48.4%), right unilateral in 12 cases (38.7%) and bilateral in 4 cases (12.9%), follow-up of the shoulder, the location of which was bilateral in 2 cases (6.4%). According to the Arlet and Ficat classification, osteonecrosis was stage III in 15 patients (47.4%), stage II in 14 patients (45.1%) and stage IV in 2 cases (6.4%). The treatment combined medical treatment in all patients and surgical treatment in 6 patients (19.3%).

Conclusion: This work underlines that osteonecrosis is a serious and disabling complication of sickle cell anemia. Adequate management involves analgesics and NSAIDs in our context.

Keywords: Osteonecrosis; Sickle Cell Disease; Hemoglobinopathy S


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Citation: Affleck Romaric Ledier Angalla., et al. “Sickle Cell Osteonecrosis, Report of 31 Cases in Congo Brazzaville”.Acta Scientific Medical Sciences 5.6 (2021): 59-63.


Copyright: © 2021 Affleck Romaric Ledier Angalla., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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