Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Case Report Volume 5 Issue 6

Panniculitis at the Site of Subcutaneous Interferon Beta Injections in a Patient with Multiple Sclerosis

Rym Sahnoun1,2, Syrine Ben-Hammamia1,2, Ons Charfi1,2, Ghozlane Lakhoua1,2, Talel Badri2,3 and Ahmed Zaiem1,2*

1Adverse Events Collection and Analysis Department, National Center of Pharmacovigilance, Tunisia
2University of Tunis-El-Manar, Faculty of Medicine, Tunisia
3Dermatology Department, Habib Thameur Hospital, Tunisia

*Corresponding Author: Ahmed Zaiem, Adverse Events Collection and Analysis Department, National Center of Pharmacovigilance, Medicine Faculty, Tunisia.

Received: February 19, 2021; Published: May 06, 202


  Interferon-β (INF-β) is associated with a high frequency of side effects, but severe local skin reactions are still rare. We report the case of complicated panniculitis induced by subcutaneous INF-β-1a injections in a 30-year-old woman, with a multiple sclerosis history. The patient developed, four years after the start of subcutaneous INF-β-1a treatment, painful erythematous ulcerated induration, which evolved into induration and fibrosis lesions. Through this case report, we would like to emphasize on the importance of preventive measures, to avoid such severe cutaneous adverse event, which may lead to lack of compliance and disease recrudescence.

Keywords: Panniculitis; Interferon Beta; Multiple Sclerosis


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Citation: Ahmed Zaiem., et al. “Panniculitis at the Site of Subcutaneous Interferon Beta Injections in a Patient with Multiple Sclerosis”.Acta Scientific Medical Sciences 5.6 (2021): 13-15.


Copyright: © 2021 Ahmed Zaiem., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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