Acta Scientific Medical Sciences (ISSN: 2582-0931)

Research Article Volume 4 Issue 8

Rate of Recurrence After Isolated Coarctation Repair: A Retrospective Study in a Single Tertiary Centre

Sami M AlAhmari1*, Khalid S Alnajashi1, Ahmed Elway2, Howida Alqethamy2, Turki AlQahtani1 and Merna M Atiyah1

1Department of Pediatric Cardiology, PSCC, Riyadh, Kingdom of Saudi Arabia
2Department of Pediatric Cardiac Surgery, PSCC, Riyadh, Kingdom of Saudi Arabia

*Corresponding Author: Sami M AlAhmari, Department of Pediatric Cardiology, Riyadh, Kingdom of Saudi Arabia.

Received: June 22, 2020; Published: July 09, 2020

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Abstract

Objectives: To retrospectively determine the incidence of recoarctation within two years of repair of isolated coarctation of the aorta in patients aged less than 14 years and operated on in our institution, and to identify the risk factors for recoarctation in our study cohort.

Methods: Review of hospital records from 1990-2016 yielded 350 patients aged less than 14 years who had undergone repair of coarctation of the aorta, 84 of whom had isolated coarctation and comprised the study cohort. We studied possible factors influencing the risk of recoarctation, including sex, delivered term or preterm, age group at diagnosis (neonate, infant, child), administration of prostaglandin E1, type of aortic valve (bicuspid, tricuspid), type of coarctation (juxtaductal, preductal, postductal), surgical approach and type of surgical procedure (end-to-end anastomosis, extended end-to-end anastomosis, subclavian flap). We use binary logistic regression to analyse associations between the above-listed patient characteristics and identify independent predictors of recoarctation requiring intervention.

Results: Reintervention by catheterisation was required within two years of surgery by 23 (27.4%) of the 84 patients with isolated coarctation, 11 of whom (47.8%) had developed recoarctation within one year of surgery. Binary logistic regression of the examined variables between those who did and did not develop recoarctation failed to identify any significant risk factors for recoarctation (χ2 (8) = 6.532, p = 0.558).

Conclusion: In our cohort, the incidence of recoarctation within two years of repair of isolated coarctation of the aorta in patients aged less than 14 years is 27.4%. We were unable to identify any risk factors for recoarctation.

Keywords: Coarctation of Aorta (COA); Prostaglandin E1 (PGE1)

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References

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Citation

Citation: Sami M AlAhmari., et al. “Rate of Recurrence After Isolated Coarctation Repair: A Retrospective Study in a Single Tertiary Centre". Acta Scientific Medical Sciences 4.8 (2020): 15-19.



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