Acta Scientific Medical Sciences (ISSN: 2582-0931)

Research Article Volume 4 Issue 6

Efficacy of Nitrofurantoin in Catheter Associated Urinary Tract Infection

Nikita Birhman1*, Sneha Mohan2 and Dalip K Kakru3

1MSc. Medical Microbiology, Department of Microbiology, School of Medical Sciences and Research, Sharda University, Greater Noida, UP, India
2Assistant Professor, Department of Microbiology, School of Medical Sciences and Research, Sharda University, Greater Noida, UP, India
3Professor, Department of Microbiology, School of Medical Sciences and Research, Sharda University, Greater Noida, UP, India

*Corresponding Author: Nikita Birhman, MSc. Medical Microbiology, Department of Microbiology, School of Medical Sciences and Research, Sharda University, Greater Noida, UP, India.

Received: April 29, 2020; Published: June 01, 2020

×

Abstract

Introduction: Catheter-associated urinary tract infection (CAUTI) is one of the most common causes of hospital-acquired infections. Nitrofurantoin, a broad-spectrum bactericidal antibiotic, is frequently used to treat UTI, including the catheter associated urinary tract infections.

Materials and Methods: 300 catheterized urine samples were received in the bacteriological laboratory during the study period. The specimens were processed as per the standard bacteriological procedures.

Results: Out of 300 samples included in this study a total of 76 strains were isolated and identified on the basis of culture characteristics, Gram’s stain and biochemical reactions. The isolates were subjected to antimicrobial susceptibility and efficacy of nitrofurantoin was analysed in various organism.

Conclusion: In the present study, we found that Nitrofurantoin (NIT) drug was more effective followed by other antibiotics. This is a welcome finding in times of increasing antibiotic resistance and is a reason enough to suggest prophylactic use of Nitrofurantoin in the health care settings when in dwelling catheters become a necessity.

Keywords: Bacteriological Profile; CAUTI; UTI

×

References

  1. SK Hasan A., et al. “Laboratory diagnosis of urinary tract infections using diagnostics tests in adult patients”. International Journal of Research in Medical Sciences 2 (2014): 415.
  2. Naveen G., et al. “Bacteriological study of Catheter Associated Urinary Tract Infection in a Tertiary Care Hospital”. International Journal of Current Microbiology and Applied Sciences 9 (2016): 640-644.
  3. Ramesh A., et al. “Microbiological profile, comorbidity, incidence and rate analysis of catheter tract infections in adult intensive care unit”. Indian Journal of Microbiology Research1 (2018): 38-43.
  4. Bagchi I., et al. “Microbiological evaluation of catheter associated urinary tract infection in a tertiary care hospital”. People’s Journal of Scientific Research2 (2015): 23-29.
  5. Patil HV and Patil VC. “Clinical, Bacteriology Profile and Antibiotic Sensitivity Pattern of Catheter Associated Urinary Tract Infection at Tertiary Care Hospital”. International Journal of Health Sciences and Research1 (2018): 25-35.
  6. Barad PS and DL Barate. “Prevalence and Antibiotic susceptibility pattern of Bacteria isolated from catheter Associated Urinary Tract Infection”. Bioscience Discovery1 (2018): 1-7.
  7. Jayasukhbhai D., et al. “Study of incidence and risk factors of urinary tract infection in catheterised patients admitted at tertiary care hospital”. International Journal of Research in Medical Sciences12 (2015): 3808.
  8. Maharajan G., et al. “Catheter Associated Urinary Tract Infection and Obstinate Biofilm Producers”. Canadian Journal of Infectious Diseases and Medical Microbiology (2018): 7624857.
  9. Kulkarni SG., et al. “Profile of urinary tract infection in indwelling catheterized patients”. IOSR Journal of Dental and Medical Sciences 4 (2014): 132-138.
  10. Bhatia N., et al. “Urinary catheterization in medical wards”. Journal of Global Infectious Diseases 2 (2010): 83-90.
  11. Bagchi I., et al. “Microbiological Evaluation of Catheter Associated Urinary Tract Infection in a Tertiary Care Hospital”. People’s Journal of Scientific Research 2 (2015): 23-29.
×

Citation

Citation: Nikita Birhman., et al. “Efficacy of Nitrofurantoin in Catheter Associated Urinary Tract Infection". Acta Scientific Medical Sciences 4.6 (2020): 158-161.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.403

Indexed In





Contact US