Acta Scientific Medical Sciences (ISSN: 2582-0931)

Case Report Volume 4 Issue 3

Sinus Cavernous Syndrome as A Presentation of Nasopharyngeal Cancer - A Case Report

Popovska H1*, Petrov I2 and Kiteva-Trencevska G2

1University Clinic of Neurology, Skopje, Macedonia
2Professor, University Clinic of Neurology, Skopje, Macedonia

*Corresponding Author: Popovska H, University Clinic of Neurology, Skopje, Macedonia.

Received: February 10, 2020; Published: February 14, 2020

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Abstract

  Nasopharyngeal cancer (NPC) is relatively rare cancer in the western world, comprising 0, 2 - 0, 5% of all cancers and 2% of all head and neck squamous cell carcinomas. Also, it is rarely implicated as a cause of cranial nerve involvement. Because of its place of origin, the nasopharynx, which is very difficult to examine, because of unspecified clinical manifestation in the early stages of the disease and because the postnasal space is frequently occupied by normal lympho-epithelium, which make the differentiation even more difficult, this type of carcinoma remain undiagnosed until the late stages of the disease. Computed tomography (CT) scan and magnetic resonance imaging (MRI) are the investigation of choice for accurate tumor mapping and detection of possible tumor extension. We report one case with a nasopharyngeal carcinoma, presenting with a syndrome of cavernous sinus, diagnosed by neurologist in the late stadium of the disease, even though there was a control examination by otorhinolaryngologist before establishing the accurate diagnosis.

Keywords: Sinus Cavernous Syndrome; Nasopharyngeal Carcinoma; Delayed Diagnosis; Magnetic Resonance Imaging (MRI)

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References

  1. Cheng K Ong and Vincent FH Chong. “Neoplasms of the Nasopharynx”. Head and Neck Cancer Imaging, edited by Robert Hermans, 2 nd ed., Springer (2012): 163-180.
  2. Keiji Tabuchi., et al. “Early Detection of Nasopharyngeal Carcinoma”. International Journal of Otolaringology (2011). 
  3. JJ Lu., et al. “Natural History, Presenting Symptoms, and Diagnosis of Nasopharyngeal Carcinoma Nasopharyngeal cancer”. Multidisciplinary menagement, edited by L.W. Brady, H.-P. Heilmann, M. Molls, C. Nieder, Springer (2010): 41-51.
  4. Ahmed M Domaa and Hanan A Gad. “The Clinical Manifestations Of Nasopharyngeal Cancer In Libya–A Comparative Study”. Middle East Journal of Applied Sciences 1.1 (2011): 1-4.
  5. Beasley P. “Anatomy of the pharynx and esophagus”. In: Michael G, editor. Scott-Brown's OtoLaryngology. 6th edition, vol.6. Oxford: Butterworth-Heinemann (1997): 1-40.
  6. Chuan TC. “Nasopharynx (The postnasal space)”. In: Hibbert J, editor. Scott-Brown's OtoLaryngolog. 6 th ed, vol.5. Oxford: Butterworth-Heinemann (1997): 1-30.
  7. Chong VFH.) Neoplasms of the nasopharynx”. In: Hermans R (ed) Head and neck cancer imaging. Springer, Berlin Heidelberg New York (2006):129-142.
  8. CK Ong and VFH Chong. “Imaging of perineural spread in head and neck tumors”. Cancer Imaging 10 (2010): S92-S98.
  9. Mehmet Turgut., et al. “Importance of cranial nerve involvement in nasopharyngeal carcinoma. Aclinical study comprising 124 cases with special reference to clinical presentation and prognosis”. Neurosurgical Review21 (1998): 243-248.
  10. Agrawal A., et al. “Nasopharyngeal Carcinoma Presenting with Cavernous Sinus Involvement, Trigeminal Neuralgia and Middle Ear Effusion”. International Journal of Clinical Pharmacy 2.4 (2009): 203-207.
  11. Marlinda Adham., et al. “Delayed diagnosis of nasopharyngeal carcinoma in a patient with early signs of unilateral ear disorder”. Medical Journal of Indonesia 23.1 (2014): 52-57.
  12. Jern-Lin Leong., et al. “Factors contributing to delayed diagnosis in nasopharyngeal carcinoma”. The Journal of Laryngology and Otology 113.7 (1999): 633-636.
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Citation

Citation: Popovska H., et al. “Sinus Cavernous Syndrome as A Presentation of Nasopharyngeal Cancer - A Case Report". Acta Scientific Medical Sciences 4.3 (2020): 01-04.



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