Abstract

Objective: Anaemia is a common complication of HIV infection affecting clinical outcome. The aim of this study was to determine the prevalence and identify factors associated with moderate to severe anaemia in HIV infected children.

Methods: This cross sectional study included 215 HIV infected children aged 6 months to 12 years. Epidemiological and clinical characteristics were recorded and a blood sample analyzed for anaemia. Multivariate logistic regression was done to determine factors associated with anaemia.

Results: Of the 215 children studied, 112 (52.1%) were males and 103 (47.9%) were females. The prevalence of anaemia was 50.7% with children aged 6 to 24 months being most affected. Factors associated with anaemia were age < 60 months (OR 4.51, p = 0.002), not taking multivitamin supplementation (OR 4.67, p = < 0.001), previous transfusion (OR 3.97,p = 0.006) and malaria co-infection (OR 4.42, p = 0.002).

Conclusions: Moderate to severe anaemia is highly prevalent among HIV infected children especially those aged 24 months and younger. HIV-infected children should be routinely evaluated for presence of anaemia, malaria prophylaxis should be stressed and more studies should be done to evaluate the impact of multivitamin supplementation on the hematological status of HIV-infected children.

Keywords: HIV-Infected; A National Referral Hospital

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Citation

Citation: Mary Munyagwa., et al. “Anaemia in HIV-Infected Children in A National Referral Hospital in Uganda: Prevalence and Associated Factors". Acta Scientific Medical Sciences 4.3 (2020): 34-40.

Copyright

Copyright: © 2020 Mary Munyagwa., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.