Department of Clinical and Experimental Biomedical Sciences “Mario Serio”, University of Florence, Italy
*Corresponding Author: Massimo Stefani, Department of Clinical and Experimental Biomedical Sciences “Mario Serio”, Italy.
Received: May 09, 2018; Published: May 30, 2018
Citation: Massimo Stefani. “Olive Polyphenols: New Possible Tools against Type 2 Diabetes and Aging-Related Neurodegeneration”. Acta Scientific Medical Sciences 2.3 (2018).
&ndsp;Increasing evidence supports the idea that olive polyphenols are effective against several aging-associated diseases, including both systemic (type 2 diabetes, atherosclerosis, stroke, the metabolic syndrome, inflammatory diseases, cancer) and neurodegenerative (Alzheimer’s and Parkinson diseases) pathologies, the latter still lacking an effective therapy [1-4]. The large literature in the field provides strong support to the benefits of the Mediterranean and Asian diets. In particular, increasing data are accumulating on the positive relation between type 2 diabetes and olive polyphenols, notably oleuropein (Ole) and its main metabolite, hydroxytyrosol (HT) . On the other hand, more recently, a solid knowledge on a claimed protection by Ole, HT and oleocanthal, a third important olive polyphenol, against Aβ plaque deposition in Alzheimer’s disease (AD) as well as on the molecular basis of the latter, has been accumulating .
Copyright: © 2018 Massimo Stefani. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.