Palanisamy Sankar¹* and Ramya Kalaivanan²

¹Department of Veterinary Pharmacology and Toxicology, Veterinary College and Research Institute, Namakkal, Tamil Nadu, India
²Department of Veterinary Microbiology, Veterinary College and Research Institute, Namakkal, Tamil Nadu, India

*Corresponding Author: Palanisamy Sankar, Department of Veterinary Pharmacology and Toxicology, Veterinary College and Research Institute, Namakkal, Tamil Nadu, India.

Received: February 22, 2018; Published: March 27, 2018

Citation: Palanisamy Sankar and Ramya Kalaivanan. “Application of Stem Cells in the New Drug Development for Evaluating the Organ Toxicity”. Acta Scientific Medical Sciences 2.1 (2018).

Abstract

&ndps;&ndps;Stem cell has opened a new avenue in the area of drug discovery and development. Stem cells are capable of renewing themselves. However, they can be continuously cultured in an undifferentiated state, giving rise to more specialized cells of the human body such as heart, liver, bone marrow, blood vessel, pancreatic islet, and nerve cells. Potential use of stem cells instead of the primary cells for the research related to the drug discovery and its screening will certainly be a resourceful tool as formulating drugs are more diverse and complex. Therefore, stem cells are an important new tool for developing unique, in vitro model systems to test drugs and chemicals and a potential to organ toxicity. This review provides an overview of the applications of stem cell in the area of organ toxicity in drug development process.

Keywords: Stem Cells; New Drug Development; Organ Toxicity

Copyright: © 2018 Palanisamy Sankar and Ramya Kalaivanan. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.