Mustafa Zaboli¹, Afifa Mehmood¹, Ghazi Abrar², Syed Faiq² and Zain Majid²*

¹Department of Radiology, Sindh Institute of Urology and Transplantation, SIUT, Pakistan
²Faculty of Medicine and Medical Sciences, University of Balamand, El-Koura, Lebanon

*Corresponding Author: Zain Majid, Department of Gastroenterology, Sindh Institute of Urology and Transplantation, SIUT, Pakistan.

Received: March 24, 2026; Published: June 22, 2026

Abstract

Invasive fungal infections (IFIs) are life-threatening systemic infections that require prompt diagnosis and treatment because they are associated with high morbidity and mortality. Approximately 1.9 million patients develop an acute invasive fungal infection each year. In addition, the global emergence of multidrug-resistant fungal species has further worsened treatment outcomes and increased mortality rates. Several fungal species demonstrate resistance to all four major classes of antifungal drugs, including polyenes, azoles, echinocandins, and the pyrimidine analogue (e.g., 5-flucytosine). Because of the limited number of antifungal agents that can be used systemically, the management of IFIs remains clinically challenging. IFI can be caused by a variety of pathogens, among which Trichosporon species are considered a rare cause. These pathogenic yeasts are widely distributed in nature and are also present as part of the normal flora of human skin, the gastrointestinal (GI) tract, and the respiratory tract. Disseminated disease caused by these organisms can involve multiple organs and may present as soft tissue lesions, lymphadenopathy, or abscesses that can mimic malignancy. Here, we report a histopathologically confirmed case of invasive fungal infection caused by the rare fungal pathogen Trichosporon in a 23-year-old male who presented with shortness of breath and weight loss. Imaging findings on CT scan initially suggested renal cell carcinoma (RCC). The patient also had a recent history of prolonged high-dose antibiotic therapy for pulmonary tuberculosis (TB).

Keywords: Invasive Fungal Infection; CT Scan; Pulmonary Tuberculosis

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Citation

Citation: Zain Majid., et al. “Invasive Fungal Infection (IFI) by Trichosporon Species Resembling Renal Mass on CT Scan: A Case Report". Acta Scientific Gastrointestinal Disorders 9.3 (2026): 32-35.

Copyright

Copyright: © 2026 Zain Majid., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.