S Yu Ignatenkov1, I Yu Kudryavtsev1,2*, KA Kuzminykh1, OA Skugareva1 and EA Dobrosotskaya2
1Kaluga Regional Clinical Oncology Center, Kaluga, Russia
2Kaluga State University Named After K.E. Tsiolkovsky, Kaluga, Russia
*Corresponding Author: EA Dobrosotskaya, Kaluga Regional Clinical Oncology Center and Kaluga State University Named After K.E. Tsiolkovsky, Kaluga, Russia.
Received: August 05, 2021; Published: August 16, 2021
Rectal cancer is one of the most common malignant tumors of the gastrointestinal tract. Recent studies have shown the high efficiency and impact of neoadjuvant chemoradiotherapy on the number of sphincter-preserving surgeries, and local regional control.
The article provides a review of the oncological literature in Russia devoted to the efficacy and safety of preoperative chemoradiation therapy against the background of hyperthermia in the treatment of locally advanced stage II-IV rectal cancer. In addition, the degree of therapeutic pathomorphosis in 59 patients of the Kaluga oncology clinic is considered, among whom 35 patients received radiosensitization only with chemotherapy and 24 patients additionally underwent local hyperthermia. The thermal radiation component use in combined treatment allows achieving an increase in the number of medical pathomorphosis of the III-IV degree.
Keywords: Rectal Cancer Stage II-IV; Combined Treatment; Chemotherapy; Radiation Therapy; Regional Hyperthermia
Citation: I Yu Kudryavtsev., et al. “Therapeutic Pathomorphosis After Thermochemoradiotherapy of the Rectal Cancer”. Acta Scientific Gastrointestinal Disorders 4.9 (2021): 29-33.
Copyright: © 2021 I Yu Kudryavtsev., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.