Amar Hegde¹ and Anand Bhandary Panambur²*

¹Resident, Department of General Surgery, A.J. Institute of Medical Sciences and Research Center, Mangalore, India
²Assitant Professor, Department of General Surgery, A.J. Institute of Medical Sciences and Research Center, Mangalore, India

*Corresponding Author: Anand Bhandary Panambur, Assitant Professor, Department of General Surgery, A.J. Institute of Medical Sciences and Research Center, Mangalore, India.

Received: June 13, 2024; Published: July 16, 2024

Abstract

Mucocele of the appendix refers to a mucus-filled appendix that may be caused by neoplastic or non-neoplastic illnesses. The most common etiology is low-grade appendiceal mucinous tumor. LAMN are rare tumors that account for <0.4-1% of all gastrointestinal malignancies. They are identified incidentally during appendectomy. Imaging alone cannot provide a good diagnosis, hence surgical excision without capsular disruption is indicated. We present the case of a 50-year-old woman who complained of right lower abdominal pain for two days. Imaging revealed a suspected acute appendicitis with periappendiceal fluid accumulation. She underwent an open appendicectomy, which revealed a massive (12 x 6 x 5 cm) mucocele, and histology confirmed it to be a LAMN with negative margins.

Keywords: Mucocele; Database; Imaging

References

1. Raijman I., et al. “Appendiceal mucocele: endoscopic appearance”. Endoscopy3 (1994): 326-328.
2. Hamilton DL and Stormont JM. “The volcano sign of appendiceal mucocele”. Gastrointestinal Endoscopy5 (1989): 453-456.
3. Connor SJ., et al. “Appendiceal tumors: retrospective clinicopathologic analysis of appendiceal tumors from 7,970 appendectomies”. Diseases of the Colon and Rectum1 (1998): 75-80.
4. Turaga KK., et al. “Importance of histologic subtype in the staging of appendiceal tumors”. Annals of Surgery Oncology 5 (2012): 1379-1385.
5. Radswiki T and Sharma R. “Appendiceal mucocele”. Reference article, Radiopaedia.org (2021).
6. Schelomo Marmor., et al. “The Rise in Appendiceal Cancer Incidence: 2000-2009”. Journal of Gastrointestinal Surgery (2015).
7. McCusker ME., et al. “Primary malignant neoplasms of the appendix: A population based study from the surveillance, epidemiology and end-results program, 1973-1998”. Cancer 94 (2002): 3307-3312.
8. Smeenk RM., et al. “Appendiceal neoplasms and pseudomyxoma peritonei: A population based study”. European Society of Surgical Oncology 34 (2008): 196-201.
9. Stocchi L., et al. “Surgical treatment of appendiceal mucocele”. Archives of Surgery6 (2003): 585-589; discussion 589-590.
10. Weerakkody Y and Ashraf A. “Low-grade appendiceal mucinous neoplasm”. Reference article,Radiopaedia.org. (2021).
11. Yousif Habib., et al. “Giant Low- Grade Appendiceal Mucinous Neoplasm in a Middle-Aged Female: A Case Report and Review of Literature”. Dubai Medical Journal (2021).
12. Nagata H., et al. “A giant mucinous cystadenocarcinoma of the appendix: a case report and review of the literature”. World Journal of Surgical Oncology 14 (2016): 64.
13. Pickhardt PJ., et al. “Primary neoplasms of the appendix: radiologic spectrum of disease with pathologic correlation”. RadioGraphics 3 (2003): 645-662.
14. Ramaswamy V. “Pathology of mucinous appendiceal tumors and pseudomyxoma peritonei”. Indian Journal of Surgical Oncology 7 (2016): 258-267.
15. Padmanaban V., et al. “Incidentally discovered low-grade appendiceal mucinous neoplasm: a precursor to pseudomyxoma peritonei”. Clinical Case Report 4 (2016): 1112-1116.
16. Montes O., et al. “Giant appendicular mucinous cystoadenoma case report and review of the literature”. Archives of Clinical Gastroenterology 2 (2016): 001-003.
17. Fujino S., et al. “Single-incision laparoscopic cecectomy for low- grade appendiceal mucinous neoplasm after laparoscopic rectectomy”. World Journal of Gastrointestinal Surgery 27 (2014): 84-87.
18. Kelly KJ. “Management of appendix cancer”. Clinics in Colon and Rectal Surgery4 (2015): 247-255.
19. Pahlavan PS and Kanthan R. “Goblet cell carcinoid of the appendix”. World Journal of Surgical Oncology 3 (2005): 36.
20. Arnason T., et al. “Significance of proximal margin involvement in low-grade appendiceal mucinous neoplasms”. Archives of Pathology and Laboratory Medicine 139 (2015): 518-521.
21. Asenov Y., et al. “Appendiceal mucocele: case report and review of the literature”. Chirurgia6 (2015): 565-569.
22. Hassan S., et al. “Appendiceal mucocele: a missed diagnosis”. BMJ Case Report 2013 (2013): bcr2012007983.
23. Bartlett C., et al. “Mucocele of the appendix: a diagnostic dilemma - a case report”. Journal of Medical Case Reports 1 (2007): 183.
24. Sunil Kumar BB and Jasuja P. “Appendiceal mucocele: a rare case report”. International Journal of Surgery Case Reports 58 (2019): 21-25.

Citation

Citation: Amar Hegde and Anand Bhandary Panambur. “A Tumor Masquerading as Appendicitis in a Middle Aged Female Turnout be a Giant Low Grade Appendiceal Mucinous Neoplasm - A Rare Case Report".Acta Scientific Clinical Case Reports 5.8 (2024): 36-40.

Copyright

Copyright: © 2024 Amar Hegde and Anand Bhandary Panambur. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.