Acta Scientific Agriculture (ASAG)(ISSN: 2581-365X)

Research Article Volume 7 Issue 11

Phytochemical and Pharmacological Studies of Traditionally Used Herbal Plants and their Potential Applications in Nutraceutical Formulations

Diksha Sharma1, Radhna Gupta2 and Farhan Mohiuddin Bhat3*

1Research Scholar, Department of Food Science Nutrition and Technology, CSK Himachal Pradesh Agricultural University, Palampur, HP, India
2Professor, Department of Food Science Nutrition and Technology, CSK Himachal Pradesh Agricultural University, Palampur, HP, India
3Assistant Professor, Department of Food Science Nutrition and Technology, CSK Himachal Pradesh Agricultural University, Palampur, HP, India

*Corresponding Author: Farhan Mohiuddin Bhat, Assistant Professor, Department of Food Science Nutrition and Technology, CSK Himachal Pradesh Agricultural University, Palampur, HP, India.

Received: August 10, 2023; Published: October 09, 2023


Herbal plants are being used for therapeutic purposes to cure diverse forms of diseases since centuries ago. Many medicinal therapists across the world utilize these herbs for the treatment of diseases, such as ayurveda and traditional Chinese medicine. The use of herbal based medicines considered as safe with no side effects have increased at an alarming pace as compared to synthetic drugs globally. Medicinal herbs have been validated to eradicate the core of diseased ailments irrespective of age group and are having lesser chances of developing adverse effects due to chemical interactions and microbial resistance as induced by most of the synthetic drugs. Considering the multiple biological activities, which are beneficial for healthy functioning of human body including prevention of cancers, inflammations, infections, antiseptics, antimicrobial, antidiarrheal, antioxidants and innumerable healing characteristics. In this study, we assessed the potential benefits and bioactive compounds present in diverse ranges of medicinal herbs, so that it could provide a valid source for practitioners and those interested in formulation of health promoting supplements and nutraceuticals. The chemical composition of medicinal herbs not only enables a researcher to enhance health by curing a specific disease but also to preserve a formulated food product with natural based remedies. Products developed from herbal combinations have been found to reduce toxicity in human body along with improving efficacy.

Keywords: Medicinal Herbs; Bioactive Composition; Pharmalogical Properties


  1. Gunjan M., et al. “Marketing trends and future prospects of herbal medicine in the treatment of various disease”. World Journal of Pharmaceutical Research 4 (2015):132-155.
  2. Wojdyło A., et al. “Antioxidant activity and phenolic compounds in 32 selected herbs”. Food Chemistry 105(2007):140-149.
  4. Yankuzo H., et al. “Beneficial effect of the leaves of Murrayakoenigii (Linn.) Spreng (Rutaceae) on diabetes-induced renal damage in vivo”. Journal of Ethnopharmacology 135(2011):88-94.
  5. Husna F., et al. “Anti-Diabetic Potential of Murrayakoenigii (L) and its Antioxidant Capacity in Nicotinamide-Streptozotocin Induced Diabetic Rats”. Drug Research (Stuttgart) 68(2018):631-636.
  6. Amna U., et al. “Evaluation of cytotoxic activity from Temurui (Murrayakoenigii [Linn.] Spreng) leaf extracts against HeLa cell line using MTT assay”. Journal of Advanced Pharmaceutical Technology and Research 10(2019):51-55.
  7. Yeap SK., et al. “Chemopreventive and immunomodulatory effects of Murrayakoenigii aqueous extract on 4T1 breast cancer cell-challenged mice”. BMC Complementary and Alternative Medicine 4(2015):306.
  8. Bhandari Prasan R. "Curry leaf (Murrayakoenigii) or cure leaf: review of its curative properties”. Journal of Medical Nutrition and Nutraceuticals2 (2012): 92.
  9. Desai SN., et al. “Hepatoprotective potential of polyphenol rich extract of Murrayakoenigii: An in vivo study”. Food and Chemical Toxicology 50(2012):310-314.
  10. Gajaria TK., et al. “Flavonoid rich extract of Murrayakoenigii alleviates in-vitro LDL oxidation and oxidized LDL induced apoptosis in raw 264.7 Murine macrophage cells”. Journal of Food Science and Technology 52(2015):3367-3375.
  11. Sestili P., et al. “The Potential Effects of OcimumBasilicum on Health: A Review of Pharmacological and Toxicological Studies”. Expert Opinion on Drug Metabolism and Toxicology 7(2018):679-692.
  12. Abdoly M., et al. “Antidepressant-like Activities of OcimumBasilicum (Sweet Basil) in the Forced Swimming Test of Rats Exposed to Electromagnetic Field (EMF)”. African Journal of Pharmacy and Pharmacology 3(2012):211-215.
  13. Khan MF., et al. “A prospective review on phyto-pharmacological aspects of Vitex negundo Linn”. Current Traditional Medicine1(2021):138-150.
  14. Neha B., et al. “Phyto-pharmacological and biological aspects of vitex negundo medicinal plant-A review”. Cardiovascular Diseases 6.7(2021).
  15. El-SaberBatiha G., et al. “Traditional uses, bioactive chemical constituents, and pharmacological and toxicological activities of Glycyrrhiza glabra (Fabaceae)”. Biomolecules10.3(2020):352.
  16. Hasan MK., et al. “Phytochemistry, pharmacological activity, and potential health benefits of Glycyrrhiza glabra”Heliyon7.6(2021):
  17. Abdel-Latif HM., et al. “Milk thistle (Silybum marianum) extract improves growth, immunity, serum biochemical indices, antioxidant state, hepatic histoarchitecture, and intestinal histomorphometry of striped catfish, Pangasianodonhypophthalmus”. Aquaculture562(2023):
  18. Jan R., et al. “Curry Leaf: An insight into its Pharmacological Activities, Medicinal Profile, and Phytochemistry”. Science of Spices and Culinary Herbs-Latest Laboratory, Pre-clinical, and Clinical Studies4(2021):145-168.
  19. McCance KR., et al. “Influence of Plant Maturity on Anthocyanin Concentrations, Phenolic Composition, and Antioxidant Properties of 3 Purple Basil (OcimumBasilicum) Cultivars”. Journal of Food Composition and Analysis 53(2016):30-39.
  20. Ilić AS., et al. “Chemical Composition of the Essential Oils of Three OcimumBasilicum Cultivars from Serbia”. NotulaeBotanicae Horti Agrobotanici Cluj-Napoca 47.2(2018):347-351.
  21. Li H., et al. “Evaluation of the Chemical Composition, Antioxidant and Anti-inflammatory Activities of Distillate and Residue Fractions of Sweet Basil Essential Oil”. Journal of Food Science and Technology 54(2017):1882-1890.
  22. Gautam LM., et al. “Chemical constituents from Vitex negundo (Linn.) of Nepalese origin”. Scientific World6(2008):27-32.
  23. Koirala N., et al.Vitex negundo: phytochemical composition, nutritional analysis, and antioxidant and antimicrobial activity”. Cellular and Molecular Biology66.4(2020):1-7.
  24. Husain A., et al. “Quantitative analysis of total phenolic, flavonoid contents and HPTLC fingerprinting for standardization of Glycyrrhiza glabra Roots”. Herbal Medicine 1(2015):1-9.
  25. Wang X., et al. “Health benefits of Silybum marianum: Phytochemistry, pharmacology, and applications”. Journal of Agricultural and Food Chemistry68.42(2020):11644-11664.
  26. Marceddu R., et al. “Milk thistle (Silybum Marianum) as a novel multipurpose crop for agriculture in marginal environments: A review”. Agronomy12.3(2022):729.
  27. Gautam S., et al. “Preprocedural Mouth Rinse in COVID-19 Era-Chemical and Phytotherapeutic Approach”. Journal of Primary Care Dentistry and Oral Health3.1(2022):
  28. Tshilanda DD., et al. “Ocimum species as potential bioresources against COVID-19: A review of their phytochemistry and antiviral activity”. International Journal of Pathogen Research5.4(2020):42-54.
  29. Mitra D., et al. “Molecular docking and simulation studies of natural compounds of Vitex negundo L. against papain-like protease (PLpro) of SARS CoV-2 (coronavirus) to conquer the pandemic situation in the world”. Journal of Biomolecular Structure and Dynamics40.12(2022):5665-5686.
  30. Armanini D., et al. “Coronavirus-19: possible therapeutic implications of spironolactone and dry extract of Glycyrrhiza glabra(licorice)”. Frontiers in Pharmacology11(2020):558418.
  31. , et al. “Inhibition of silibinin on migration and adhesion capacity of human highly metastatic breast cancer cell line, MDA-MB-231, by evaluation of beta1-integrin and downstream molecules, Cdc42, Raf-1 and D4GDI”. Medical Oncology 29.4(2012):2512-518.v
  32. Purohit P and Mishra B. Journal of Pharmacy Research 16(2017):86-94.


Citation: Farhan Mohiuddin Bhat., et al. “Phytochemical and Pharmacological Studies of Traditionally Used Herbal Plants and their Potential Applications in Nutraceutical Formulations". Acta Scientific Agriculture 7.11 (2023): 26-41.


Copyright: © 2023 Farhan Mohiuddin Bhat.,et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate32%
Acceptance to publication20-30 days
Impact Factor1.014

Indexed In

News and Events

  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is July 30, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US