Retro Synthetic Approach on Synthesis of Quinoline Derivative Using Microwave Energy

S Ravichandran¹*, Sayeeda Sultana², G Jagadeeswarao² and S Suresh³

¹ Department of Chemistry, Lovely Professional University, Punjab, India
²St Peter’s Institute of Higher Education and Research, Avadi, Chennai, India
³Department of Chemistry, St. Martin’s Engineering College, Secunderabad, India

*Corresponding Author: S Ravichandran, Department of Chemistry, Lovely Professional University, Punjab, India.

Received: January 20, 2022; Published:

Abstract

In the present study an attempt has been made to synthesize quinoline derivative by retrosynthetic method. The fact that every synthesis involves different routes and is reflected in the property of final product The present work replaces conventional heating method by microwave energy to isolate substituted quinolines. The reterosynthesised material is subjected to characterization by spectral techniques and its anti-microbial activities has also been evaluated. Results obtained clearly indicates that retrosynthetic product scores over conventional heating procedure in respect of its purity and anti-microbial activity.

 

Keywords: Retrosynthetic Products; Quinoline; Antimicrobial Activity

References

1. TM Gøgsig., et al. Organic Letters 11 (2009): 4886-4888.
2. OV Larionov., et al. Organic Letters 16 (2014): 864-867.
3. R Yan., et al. Organic Letters 15 (2013): 4876-4879.
4. R Sarma and D Prajapati. Synlett (2008): 3001-3005.
5. Z Wang., et al. The Journal of Organic Chemistry 77 (2012): 8615-8620.
6. S Khong and O Kwon. The Journal of Organic Chemistry 77 (2012): 8257-8267.
7. H Batchu S., et al. Organic Letters 14 (2012): 6330-6333.
8. X Jia., et al. Org. Lett 14 (2012): 4030-4033.
9. Y Zhang., et al. Organic Letters 14 (2012): 2206-2209.
10. G Shan., et al. Organic Letters 13 (2011): 5770-5773.
11. KC Lekhok., et al. Synlett (2008): 655-658.
12. NT Patil and VS Raut. The Journal of Organic Chemistry 75 (2010): 6961-6964.
13. B Das., et al. Synthesis (2011): 3267-3270.
14. A Kumar and VK Rao. Synlett (2011): 2157-2162.
15. N Sakai., et al. Organic Letters 14 (2012): 836-839.
16. T Mitamura., et al. The Journal of Organic Chemistry 76 (2011): 1163-1166.
17. Z Zhang., et al. Organic Letters 10 (2008): 173-175.
18. R Martinez., et al. The Journal of Organic Chemistry 73 (2008): 9778-9780.
19. RP Korivi., et al. The Journal of Organic Chemistry 71 (2006): 7079-7082.
20. RG Xing., et al. Synthesis (2011): 2066-2072.
21. MJ Sandelier and P DeShong. Org. Lett 9 (2007): 3209-3212.
22. GL Gao., et al. The Journal of Organic Chemistry 75 (2010): 1305-1308.
23. Z Huo., et al. The Journal of Organic Chemistry 75 (2010): 1266-1270.
24. H Huang., et al. The Journal of Organic Chemistry 74 (2009): 5476-5480.
25. KK Toh., et al. Organic Letters 14 (2012): 2290-2292.
26. M Movassaghi., et al. Journal of the American Chemical Society 128 (2006): 4592-4593.
27. AE Wendlandt and SS Stahl. Journal of the American Chemical Society 136 (2014): 11910-11913.
28. B Liu., et al. The Journal of Organic Chemistry 78 (2013): 10319-10328.
29. Pathan SI., et al. Synthetic Communications 50 (2020): 1251-1285.
30. Matada BS and Yernale NG. Synthetic Communications 51 (2021): 1133-1159.
31. Sharma R., et al. Journal of Chemical Sciences 130 (2018): 73.
32. Li H., et al. Chemical Communications 53 (2017): 5993-5996.

Citation

Citation: S Ravichandran., et al. “Retro Synthetic Approach on Synthesis of Quinoline Derivative Using Microwave Energy". Acta Scientific Agriculture 6.5 (2022): 03-07.

Copyright

Copyright: © 2022 S Ravichandran., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.