Antimicrobial Potential of Green Synthesized Gold Nano-Particles Against Human Pathogens

Swati Sharma¹, Damanjeet Kaur², Saurabh Gupta²*, Ajay Singh³ and Kamalpreet Kaur³

¹Department of Biotechnology, Mata Gujri College, Fatehgarh Sahib, Punjab, India
²Department of Microbiology, Mata Gujri College, Fatehgarh Sahib, Punjab, India
³Department of Food Technology, Mata Gujri College, Fatehgarh Sahib, Punjab, India

*Corresponding Author: Saurabh Gupta, Assistant Professor, Department of Microbiology, Mata Gujri College, Fatehgarh Sahib, Punjab,India.

Received: July 16, 2018; Published: July 27, 2018

Citation: Saurabh Gupta., et al. “Antimicrobial Potential of Green Synthesized Gold Nano-Particles Against Human Pathogens". Acta Scientific Agriculture 2.8 (2018).

Abstract

  Green synthesis is a novel approach for the biogenesis of nano-particles- tiny structures having enormous applications. In the current study, fungal strains were explored for their ability to biosynthesize both intra- and extracellular gold nano-particles. Out of twelve, four fungal strains namely SSG-2, SSG-5, SSG-8 and SSG-11 were selected on the basis of development of varied colors in cell free supernatant and fungal beads upon exposure with tetra-chloroauric acid. Crystallographic characterization of biomass associated, and cell free nano-particles were carried out by X-Ray Diffraction (XRD) and UV-Visible spectroscopy. A wide variation in crystallite size for intracellular and extracellular nano-particles has been observed. Further these intra- and extracellular nano-particles exhibited intense antimicrobial activities against human pathogens.

Keywords: Green Synthesis; Nano-Particles; XRD (X-Ray Diffraction); Antimicrobial; Tetra-Chloroauric Acid

Copyright: © 2018 Peng Chen., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.