Abstract

Aim: The aim of this study is to determine the prescribing patterns of Non-steroidal anti-inflammatory drugs in different inpatient departments and assessing probable drug interactions.

Methodology: It is a prospective observational study for over a period of 6 months, data was collected from the case sheets of patients those are prescribed with the variety of NSAID’s.

Results: Our study reported 260 subjects of which 133 (51.15%) and 127 (48.85%) were males and females respectively. Majority of the patients were admitted to the Female Medical Ward (FMW) 59 (46.46). The commonest clinical indications for prescribing NSAIDs was Lower backache (LBA) 36 (13.85%) followed by others. Most frequently prescribed NSAID was diclofenac 157 (42.32%) followed by aceclofenac 76 (20.48%), paracetamol 60 (16.17%), etc. The drug-drug interactions identified was categorized into three different sets, major (10.46%) moderate (74.06%) and minor (15.48%).

Conclusion: Based on the obtained results we conclude that the monotherapy with single NSAID was preferred mode of therapy via parenteral or oral therapy and GPA’s should be co-prescribed for prevention from complications and there is a need to implement continuous monitoring of the drug interactions is to be prioritized to prevent adverse drug reactions which are major concern of drug interaction effects with the NSAID’s.

Keywords: NSAID; DDI; GPA; FMW; LBA

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Citation

Citation: RaviTeja Pappala., et al. “A Clinical Study on Prescribing Patterns of NSAIDs and Assessment of Drug InteractionsActa Scientific Pharmaceutical Sciences 4.5 (2020): 83-87.

Copyright

Copyright: © 2020 RaviTeja Pappala., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.