Ethnobotanical Insights into Ulcer Management
Firoj A Tamboli1*, Archana P Agale2, Tanzila R Bhagwan2, Suhani S Gonugade2, Aditya B Ambi2, Anjali R Jadhav2, Ravina M Choudhary2, Meghana S Chavan2 and Nikita V Khatal2
Faculty of Pharmacy, The Maharaja Sayajirao University of Baroda, 390001, Vadodara, Gujarat, India
*Corresponding Author: Firoj A Tamboli, Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Near Chitranagari, Kolhapur – 416013, Maharashtra, India.
Received:
September 22, 2025; Published: October 13, 2025
Abstract
Ulcers are a frequent gastrointestinal condition which is experienced by many people. It is essentially an inflamed lesion on the skin or the mucus membrane of the alimentary tract. Ulceration can occur when the established balance (homeostasis) is disrupted either by excessive aggression or reduced mucosal resistance. This may be owing to factors such as the repeated use of drugs, unordered diets, or stress, and many factors. Of these conditions, peptic ulcers are some of the most common gastrointestinal conditions in the world. The underlying cause of peptic ulceration, or the aetiology, involves multiple factors acting together including: an infection from H. pylori organism; prolonged use of non-steroidal anti-inflammatory drugs (NSAIDs); stress; alcohol; smoking; and others. The ulceration will occur due to the presence of acid and peptic activity present in gastric juice plus an impairment in the defence mechanisms of the mucosa. There are number of synthetic medications available for the treatment of ulcers; however these s medications can be expensive and can have more side-effects compared to herbal medications .The review of the literature shows that numerous medicinal plants and polyherbal formulations are utilized by various ayurvedic doctors and traditional practitioner for the management of ulcer. The optimal therapeutic goals for treating peptic ulcer disease are relieving pain, healing the ulcer, and delaying the recurrence of the ulcer. In this review, efforts have been made to learn about some of the several medicinal plants that may be utilized in ayurvedic or modern scientific treatment or prevention of peptic ulcer disease. The review covers pathophysiology, types, causes, symptoms, diagnosis, prevention and management strategies, and dietary plants for ulcers, including discussion of significant advances and future prospects.
Keywords: Ulcer; H. Pylori; NSAIDs; PPIs; Peptic Ulcer; Gastric Defense Factors
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