Kartikay Prakash²*, Shashank Tiwari¹ and Vishal Mishra³

¹Director (Academic and Research), Lucknow Model College of Pharmacy, Lucknow, Uttar Pradesh, India
²Assistant Professor, Lucknow Model College of Pharmacy, Lucknow, Uttar Pradesh, India
³Student (B. Pharm Final Year), Lucknow Model College of Pharmacy, Lucknow, Uttar Pradesh, India

*Corresponding Author: Kartikay Prakash, Assistant Professor, Lucknow Model College of Pharmacy, Lucknow, Uttar Pradesh, India.

Received: February 06, 2025; Published: February 23, 2025

Abstract

Background: You know those annoying lines on the skin when you've gained or lost weight too quickly? Yeah, those are stretch marks. This study is all about making a cream using Shata Dhauta Ghrit, a fancy Ayurvedic thing, to see if it can actually help get rid of those marks.

Aim: The research endeavors to develop a safe and effective herbal solution for diminishing stretch marks, leveraging the potential of Shata Dhauta Ghrit. This formulation aims to offer a natural alternative to conventional treatments, addressing the need for holistic skincare options.

Material and Method: Shata Dhauta Ghrit was utilized as the active pharmaceutical ingredient (API) in the formulation of a herbal stretch marks reduction cream, alongside complementary base ingredients. The cream formulation was prepared using standardized procedures, incorporating Shata Dhauta Ghrit at optimized concentrations and blending it with other constituents to ensure efficacy and safety.

Result: The formulated herbal stretch marks reduction cream demonstrated promising results in reducing the appearance of stretch marks, suggesting its potential as a natural remedy for this common dermatological concern.

Conclusion: The utilization of Shata Dhauta Ghrit as an active pharmaceutical ingredient (API) in the formulation of the herbal stretch marks reduction cream proved to be effective in reducing the appearance of stretch marks. The results of this study support the feasibility and potential of this herbal formulation as a safe and natural remedy for managing stretch marks, providing a promising avenue for further research and development in the field of herbal skincare products.

Keywords: Herbal Stretch Marks reduction Cream; Stretch Marks; Shata Dhauta Ghrit and Pregnancy

References

1. Roli Karole., et al. “Multi-Response Optimization in the Formulation of a Topical Cream from Natural Ingredients”. European Chemical Bulletin7 (2018): 1-14.
2. Kajal V Thool and G R Dixit. “Topical drug delivery system: formulation and evaluation of cream”. World Journal of Pharmaceutical Research 10.11 (2021): 427-426.
3. Mohiuddin AK., et al. “Skin Care Creams: Formulation and Use”. OSP Journal of Clinical Trials1 (2019): 1-22.
4. Chauhan Lalita Gupta S. “Creams: A Review on Classification, Preparation Methods, Evaluation and its Applications”. Journal of Drug Delivery and Therapeutics5 (2020): 281-289.
5. Laxmi Banjare and Pranita Kashyap. “Formulation and Evaluation of herbal multipurpose cream”. International Journal of Pharmacy and Therapeutics1 (2014): 5-8.
6. Richa Yadav., et al. “Formulation and Evaluation of a Moisturizing Day Cream Containing Olive Leaves Extract”. International Journal of Pharmaceutical Research and Applications3 (2023): 502-510.
7. Karade Dhirajkumar Dadasaheb and Tushar Aakhare. “Formulation and Evaluation of Multipurpose herbal cream”. International Journal of Creative Research Thoughts (IJCRT)12 (2021): c162-c169.
8. Shailesh Kumar Gupta., et al. “Formulation and Evaluation of aloevera cold cream”. International Journal of Novel Research and Development6 (2023): d524-d530.
9. Ashwini Vitthal Dubule., et al. “Review on Formulation and Evaluation of Multipurpose Herbal Cream”. International Journal of Research Publication and Reviews3 (2023): 1947-1952.
10. Supriya Deshpande., et al. “Shata- dhauta- ghrita – A case study”. Indian Journal of Traditional Knowledge3 (2009): 387-391.
11. Rani S., et al. “Formulation, Evaluation Optimization and Evaluation of Dendricream for wound healing activity of Artemisia Indica”. World Journal of Pharmacy and Pharmaceutical Sciences8 (2016): 14831497.
12. Nicander I., et al. “Baseline electrical impedance measurements at various skin sites- related to age and gender”. Skin Research Technology 3 (1997): 252-258.
13. Aswal A., et al. “Preparation and evaluation of polyherbal cosmetic cream”. Der Pharmacia Lettre1 (2013): 838.
14. Esimone CO., et al. “Factors affecting wound healing”. Journal of Pharma Allied Sciences 1 (2005): 294-299.
15. Sawalha S., et al. “Characterization of Phenolic Compounds in diatomaceous earth used in the filtrationprocess of olive oil by HPLCCES-TOF (MS)”. Journal of Agro Food Industry Hi-tech 20 (2009): 46-50.
16. Baby AR., et al. “Development of Cosmetic Mask Formulations”. Revista Brasileira de Ciências Sociais (2004).
17. Farm Ahmed SA and M Grainage. “Use of indigenous plant resources in rural development, potential of neem tree”. International Journal of Technology and Design Education 3 (1985): 123-130.
18. Quddus MA. “The cropland agroforestry experiences of the village and farm forestry project in Northwest Bangladesh”. Proceedings of the National Workshop, September 16-17, 2001, Gazipur, Bangladesh (2001): 229-239.
19. Fallah A., et al. “Effects of blending method of livestock compost with soil and mixing it with chemical compost on yield and parts of yield of seed corn in Khorramabad”. Lorestan Agric. Nat. Resour. Sci. Magaz., 40 (2006): 233-242.
20. Pooley RJ and Peterson LR. “Mechanisms of microbial susceptibility and resistance to antimicrobial agents”. In The Biologic and Clinical Basis of Infectious Diseases, (5^th Editors ST, Shulman JP, Phair LR, Peterson JR (1997): 550.
21. Roshan Telrandhe., et al. “Formulation and Evaluation of herbal toothpaste compared with marketed preparation”. International Journal of Pharmaceutics and drug Analysis10 (2007).
22. Ansari M., et al. “Development of a Simple Green Extraction Procedure and HPLC Method for determination of Oleuropein in Olive Leaf Extract Applied to a Multi-Source Comparative Study”. Journal of the Iranian Chemical Society 8 (2011): 38-47.
23. Nasrollahi SA., et al. “Comparison of linoleic acid-containing water-in-oil emulsion with urea-containing water-in-oil emulsion in the treatment of atopic dermatitis: a randomized clinical trial”. Clinical, Cosmetic and Investigational Dermatology 11 (2018): 21-28.
24. Raymond C Rowe. “Handbook of Pharmaceutical Excipients”. 6^th edition, Pharmaceutical Press (2009).
25. Czarnowicki T., et al. “Petrolatum: Barrier repair and antimicrobial responses underlying this "inert" moisturizer”. Journal of Allergy and Clinical Immunology 137 (2016): 1091-1102.
26. Halevi S and Shai A. “Chapter 3. Principles in the Preparation of Medical and Cosmetic Products”. In: handbook of Cosmetic Skin Care, 2nd Ed, Informa Health Care, 2009: Cosmetic Skin Care, 2009 Volume 1 of handbook of Cosmetic Skin Care, published by Bukupedia (2009): 20.
27. Galen (Author), Peter N. Singer (Translator). Selected Works (Oxford World's Classics), published by Oxford University Press; New edition (2002).
28. Burke KE., et al. “Effects of topical and oral vitamin E on pigmentation and skin cancer induced by ultraviolet irradiation in Skh:2 hairless mice”. Nutritional Cancer. 38 (2000): 87-97.
29. Swarbrick J., et al. “Chapter 22. Coarse Dispersions”. In: Remington: The Science and Practice of Pharmacy Volume 1, edited by David B. Troy, Paul Beringer, published by Lippincott Williams and Wilkins (2006).
30. Egawa M., et al. “Effect of exposure of human skin to a dry environment”. Skin Research Technology 8 (2002): 212-218.

Citation

Citation: Kartikay Prakash., et al. “Formulation and Evaluation of Herbal Stretch Marks Reduction Cream by Using Shata Dhauta Ghrit as an API". Acta Scientific Pharmaceutical Sciences 9.3 (2025): 48-54.

Copyright

Copyright: © 2025 Kartikay Prakash., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.